PA2G4/EBP1 Products

Description

EBP1 encodes an RNA-binding protein that is involved in growth regulation. This protein is present in pre-ribosomal ribonucleoprotein complexes and may be involved in ribosome assembly and the regulation of intermediate and late steps of rRNA processing. This protein can interact with the cytoplasmic domain of the ErbB3 receptor and may contribute to transducing growth regulatory signals. This protein is also a transcriptional co-repressor of androgen receptor-regulated genes and other cell cycle regulatory genes through its interactions with histone deacetylases. This protein has been implicated in growth inhibition and the induction of differentiation of human cancer cells. Six pseudogenes, located on chromosomes 3, 6, 9, 18, 20 and X, have been identified.

Bioinformatics

Entrez	5036 Human
Uniprot	AAH01951 Human AAH07561 Human NM_006191 Human NP_006182.2 Human Q9UQ80 Human
Product By Gene ID	5036
Alternate Names	Cell cycle protein p38-2G4 homolog EBP1 ErbB-3 binding protein 1 ErbB3-binding protein 1 ErbB3-binding protein Ebp1 HG4-1 hG4-1 p38-2G4 proliferation-associated 2G4, 38kD proliferation-associated 2G4, 38kDa proliferation-associated protein 2G4

Research Areas for PA2G4/EBP1

Find related products by research area and learn more about each of the different research areas below.

Cell Cycle and Replication
Core ESC-Like Genes
Stem Cell Markers