PA2G4/EBP1 Antibody (OTI1D3) [Alexa Fluor™ Plus 555]

• Reactivity: Hu, Mu, Rt
• Applications: WB
• Clone: OTI1D3
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: Alexa Fluor Plus 555

PA2G4/EBP1 Antibody (OTI1D3) [Alexa Fluor™ Plus 555] Summary

• Immunogen: Full length human recombinant protein of human PA2G4 (NP_006182) produced in HEK293T cell.
• Isotype: IgG1
• Clonality: Monoclonal
• Host: Mouse
• Gene: PA2G4
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • Western Blot
• Application Notes: Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

• Storage: Store at 4C in the dark.
• Buffer: 50mM Sodium Borate
• Preservative: 0.05% Sodium Azide
• Purity: Immunogen affinity purified

Notes

This product is provided under an intellectual property license from Life Technologies Corporation. The transfer of this product is conditioned on the buyer using the purchased product solely in research conducted by the buyer, excluding contract research or any fee for service research, and the buyer must not (1) use this product or its components for (a) diagnostic, therapeutic or prophylactic purposes; (b) testing, analysis or screening services, or information in return for compensation on a per-test basis; or (c) manufacturing or quality assurance or quality control, and/or (2) sell or transfer this product or its components for resale, whether or not resold for use in research. For information on purchasing a license to this product for purposes other than as described above, contact Life Technologies Corporation, 5781 Van Allen Way, Carlsbad, CA 92008 USA or outlicensing@thermofisher.com. This conjugate is made on demand. Actual recovery may vary from the stated volume of this product. The volume will be greater than or equal to the unit size stated on the datasheet.

Alternate Names for PA2G4/EBP1 Antibody (OTI1D3) [Alexa Fluor™ Plus 555]

• Cell cycle protein p38-2G4 homolog
• EBP1
• ErbB-3 binding protein 1
• ErbB3-binding protein 1
• ErbB3-binding protein Ebp1
• HG4-1
• p38-2G4
• PA2G4
• proliferation-associated 2G4, 38kD
• proliferation-associated 2G4, 38kDa
• proliferation-associated protein 2G4

Background

EBP1 encodes an RNA-binding protein that is involved in growth regulation. This protein is present in pre-ribosomal ribonucleoprotein complexes and may be involved in ribosome assembly and the regulation of intermediate and late steps of rRNA processing. This protein can interact with the cytoplasmic domain of the ErbB3 receptor and may contribute to transducing growth regulatory signals. This protein is also a transcriptional co-repressor of androgen receptor-regulated genes and other cell cycle regulatory genes through its interactions with histone deacetylases. This protein has been implicated in growth inhibition and the induction of differentiation of human cancer cells. Six pseudogenes, located on chromosomes 3, 6, 9, 18, 20 and X, have been identified.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: PA2G4