Western Blot: p53 DINP1 Antibody [NBP1-76638] - Western blotting showing TP53INP1 protein levels in NIH-H460 cells treated LNA-663. TUBULIN was used as protein loading control. Image collected and cropped by CiteAb from ...read more
Immunohistochemistry-Paraffin: p53 DINP1 Antibody [NBP1-76638] - Mouse liver using p53DINP1 antibody at 2 ug/ml.
Western Blot: p53 DINP1 Antibody [NBP1-76638] - Expression in human lung tissue lysate with p53DINP1 antibody at (A) 0.5 and (B) 1 u/mL.
Immunofluorescence: p53 DINP1 Antibody [NBP1-76638] - Staining of p53DINP1 in human liver tissue with p53DINP1 antibody at 5 ug/ml.
Antibody was raised with a synthetic peptide corresponding to 14 amino acids near the amino terminus of human p53DINP1. The immunogen is located within the first 50 amino acids of p53DINP1. Amino Acid Squence: MFQYLNKMFVGEVS
At least two isoforms of p53DINP1 are known to exist; this antibody will detect both isoforms.
Peptide affinity purified
Test in a species/application not listed above to receive a full credit towards a future purchase.
30 kDa. Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
0.02% Sodium Azide
Peptide affinity purified
Alternate Names for p53 DINP1 Antibody - BSA Free
P53DINP1p53-dependent damage-inducible nuclear protein 1
tumor protein p53 inducible nuclear protein 1
tumor protein p53-inducible nuclear protein 1
Apoptosis is related to many diseases and development. The p53 tumor-suppressor protein induces apoptosis through transcriptional activation of several genes. A novel p53 inducible gene was identified recently and designated p53DINP1 (for p53-dependent damage-inducible nuclear protein 1) and SIP (for stress induced protein) in human and mouse. A p53DINP1 antisense oligonucleotide inhibits and overexpression of p53DINP1 enhances Ser46 phosphorylation of p53, induction of p53AIP1, and cell death induced by DNA double-strand breaks. p53DINP1 may regulate p53-dependent apoptosis through phosphorylation at Ser46 and induction of p53AIP1. The p53DINP1/SIP gene encodes two proteins of 27 and 18 kDa in human and mouse termed p53DINP1-alpha and p53DINP1-beta or SIP27 and SIP18. p53DINP1/SIP is expressed in many tissues and induced by a variety of stress agents including UV stress, mutagenic stress, heat shock, and oxidative stress.
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.
The concentration calculator allows you to quickly calculate the volume, mass or concentration of your vial. Simply enter your mass, volume, or concentration values for your reagent and the calculator will determine the rest.