p53 DINP1 Products

p53 DINP1 Antibody
p53 DINP1 Antibody
Species: Hu, Mu, Rt
Applications: WB, ELISA, IHC, IHC-P, ICC/IF
Host: Rabbit Polyclonal
p53 DINP1 Antibody
p53 DINP1 Antibody
Species: Hu, Mu, Rt
Applications: WB
Host: Rabbit Polyclonal
p53 DINP1 Antibody
p53 DINP1 Antibody
Species: Hu
Applications: ICC/IF, IHC, IHC-P
Host: Rabbit Polyclonal
p53 DINP1 Overexpression Lysa ...
p53 DINP1 Overexpression Lysate (N...
Species: Hu
Applications: WB
p53 DINP1 Recombinant Protein ...
p53 DINP1 Recombinant Protein Antigen
Species: Hu
Applications: AC
p53 DINP1 Blocking Peptide
p53 DINP1 Blocking Peptide
Species: Hu
Applications: AC


Apoptosis is related to many diseases and development. The p53 tumor-suppressor protein induces apoptosis through transcriptional activation of several genes. A novel p53 inducible gene was identified recently and designated p53DINP1 (for p53-dependent damage-inducible nuclear protein and SIP (for stress induced protein) in human and mouse. A p53DINP1 antisense oligonucleotide inhibits and overexpression of p53DINP1 enhances Ser46 phosphorylation of p53, induction of p53AIP1, and cell death induced by DNA double-strand breaks. p53DINP1 may regulate p53-dependent apoptosis through phosphorylation at Ser46 and induction of p53AIP1. The p53DINP1/SIP gene encodes two proteins of 27 and 18 kDa in human and mouse termed p53DINP1-a and p53DINP1-b or SIP27 and SIP18. p53DINP1/SIP is expressed in many tissues and induced by a variety of stress agents including UV stress, mutagenic stress, heat shock, and oxidative stress.


Uniprot Human
Product By Gene ID 94241
Alternate Names
  • tumor protein p53-inducible nuclear protein 1
  • TP53INP1B
  • p53-inducible p53DINP1
  • TP53INP1A
  • TP53DINP1
  • FLJ22139
  • p53DINP1
  • DKFZp434M1317
  • P53DINP1p53-dependent damage-inducible nuclear protein 1
  • SIPStress-induced protein
  • Teap
  • tumor protein p53 inducible nuclear protein 1

Research Areas for p53 DINP1

Find related products by research area and learn more about each of the different research areas below.

Checkpoint signaling
DNA Double Strand Break Repair
DNA Repair

PTMs for p53 DINP1

Learn more about PTMs related to p53 DINP1.


Bioinformatics Tool for p53 DINP1

Discover related pathways, diseases and genes to p53 DINP1. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
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