Osteoprotegerin/TNFRSF11B Antibody (5G2)

Images

 
Western Blot: Osteoprotegerin/TNFRSF11B Antibody (5G2) [NBP1-51670] - Western blot analysis using TNFRSF11B mAb against HEK293 (1) and TNFRSF11B-hIgGFc transfected HEK293 (2) cell lysate.
Immunocytochemistry/ Immunofluorescence: Osteoprotegerin/TNFRSF11B Antibody (5G2) [NBP1-51670] - Immunofluorescence analysis of HL-60 cells using TNFRSF11B mouse mAb (green). Blue: DRAQ5 fluorescent DNA dye.
Immunohistochemistry-Paraffin: Osteoprotegerin/TNFRSF11B Antibody (5G2) [NBP1-51670] - breast cancer tissues (left) and liver cancer tissues (right) using BECN1 mouse mAb with DAB staining.
Flow Cytometry: Osteoprotegerin/TNFRSF11B Antibody (5G2) [NBP1-51670] - Flow cytometric analysis of HL-60 cells using TNFRSF11B mouse mAb (green) and negative control (purple).

Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB, ELISA, Flow, ICC/IF, IHC-P
Clone
5G2
Clonality
Monoclonal
Host
Mouse
Conjugate
Unconjugated

Order Details

Osteoprotegerin/TNFRSF11B Antibody (5G2) Summary

Immunogen
Purified recombinant fragment of human TNFRSF11B expressed in E. Coli.
Isotype
IgG1
Clonality
Monoclonal
Host
Mouse
Gene
TNFRSF11B
Purity
Unpurified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Western Blot 1:500-1:2000
  • ELISA 1:10000
  • Flow Cytometry 1:200 - 1:400
  • Immunocytochemistry/Immunofluorescence 1:200-1:1000
  • Immunohistochemistry-Paraffin
Theoretical MW
60 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Reactivity Notes

Human

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
Ascites
Preservative
0.03% Sodium Azide
Purity
Unpurified

Alternate Names for Osteoprotegerin/TNFRSF11B Antibody (5G2)

  • OCIF
  • OCIFMGC29565
  • OPGtumor necrosis factor receptor superfamily member 11B
  • Osteoclastogenesis inhibitory factor
  • Osteoprotegerin
  • TNFRSF11B
  • TR1
  • tumor necrosis factor receptor superfamily, member 11b

Background

The protein encoded by this gene is a member of the TNF-receptor superfamily. This protein is an osteoblast-secreted decoy receptor that functions as a negative regulator of bone resorption. This protein specifically binds to its ligand, osteoprotegerin ligand, both of which are key extracellular regulators of osteoclast development. Studies of the mouse counterpart also suggest that this protein and its ligand play a role in lymph-node organogenesis and vascular calcification. Alternatively spliced transcript variants of this gene have been reported, but their full length nature has not been determined. [provided by RefSeq]

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Video Protocols

WB Video Protocol
ICC/IF Video Protocol

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Secondary Antibodies

 

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Diseases for Osteoprotegerin/TNFRSF11B Antibody (NBP1-51670)

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Bioinformatics

Gene Symbol TNFRSF11B
Entrez