OATP1B1/OATP2 Antibody (ESL)

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Product Details

Summary
Reactivity Hu, Ca(-), Mu(-), Rt(-)Species Glossary
Applications WB, Flow, IHC, IHC-Fr, IHC-P, IP, ICC/IF
Clone
ESL
Clonality
Monoclonal
Host
Mouse
Conjugate
Unconjugated

Order Details

OATP1B1/OATP2 Antibody (ESL) Summary

Immunogen
Synthetic peptide corresponding to residues E(671) S L N K N K H F V P S A G A D S E T H C(691) of human OATP2.
Localization
Cell Membrane; multi pass membrane protein
Specificity
OATP2 (ESL)
Isotype
IgM
Clonality
Monoclonal
Host
Mouse
Gene
SLCO1B1
Purity
Unpurified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Western Blot 1:1000
  • Flow Cytometry 1:10 - 1:1000
  • Immunohistochemistry 1:10 - 1:500
  • Immunohistochemistry-Frozen 1:10 - 1:500
  • Immunohistochemistry-Paraffin 1:10 - 1:500
  • Immunoprecipitation 1:10 - 1:500
  • Immunofluorescence 1:100
Application Notes
Flow usage was reported in scientific literature (PMID: 25916617). IF: Staining of OATP2 in human liver samples results in a pattern consistent with plasma membrane staining.
Publications
Read Publications using
NB100-74481 in the following applications:

  • 1 publication
  • WB
    1 publication

Packaging, Storage & Formulations

Storage
Store at -20C. Avoid freeze-thaw cycles.
Buffer
Tissue culture supernatant
Preservative
0.09% Sodium Azide
Purity
Unpurified

Alternate Names for OATP1B1/OATP2 Antibody (ESL)

  • HBLRR
  • Liver-specific organic anion transporter 1
  • LST1
  • LST1SLC21A6
  • LST-1Solute carrier family 21 member 6
  • OATP1B1
  • OATP1B1Sodium-independent organic anion-transporting polypeptide 2
  • OATP2
  • OATP2MGC133282
  • OATPC
  • OATP-COATP-2
  • OATPCsolute carrier organic anion transporter family member 1B1
  • SLC01B1
  • SLC21A6
  • SLCO1B1
  • SO1B1
  • solute carrier family 21 (organic anion transporter), member 6
  • solute carrier organic anion transporter family, member 1B1

Background

The OATPs (organic anion transporter polypeptides) are a family of transport proteins that have been found to mediate the uptake of organic ions into hepatocyte cells. These proteins fall into the solute carrier family 21A (SLC21A), and are expressed in liver, kidney, and brain. These polypeptides are involved in the excretion of potentially toxic compounds and therefore play a role in the overall detoxification system of the body. Unlike other members of the OATP family, OATP2 and 8 have been detected exclusively in the liver, and there is an 80% amino acid sequence homology between these polypeptides. Other names for OATP2 include SLC21A6, OATP-C, and LST-1.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Publications for OATP1B1/OATP2 Antibody (NB100-74481)(3)

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Bioinformatics

Gene Symbol SLCO1B1
Entrez