Nuf2 Antibody (8B7) - BSA Free

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Western Blot: Nuf2 Antibody (8B7) [NBP3-26452] - Positive Western Blot detected in: Hela whole cell lysate, U251 whole cell lysate. All lanes: Nuf2 Antibody at 1: 2000 Secondary: Goat polyclonal to rabbit IgG at 1/50000 ...read more

Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB, ELISA
Clone
8B7
Clonality
Monoclonal
Host
Rabbit
Conjugate
Unconjugated
Format
BSA Free

Order Details

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Catalog# & Formulation Size Price

Nuf2 Antibody (8B7) - BSA Free Summary

Additional Information
Recombinant monoclonal antibody expressed in HEK293F cells
Immunogen
A synthesized peptide derived from Human Nuf2 [UniProt Q9BZD4]
Isotype
IgG
Clonality
Monoclonal
Host
Rabbit
Gene
NUF2
Purity
Affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • ELISA
  • Western Blot 1:500-1:2000

Packaging, Storage & Formulations

Storage
Store at -20 to -70C. Avoid freeze-thaw cycles.
Buffer
PBS, pH 7.4, 150mM NaCl, and 50% glycerol
Preservative
0.02% Sodium Azide
Purity
Affinity purified

Alternate Names for Nuf2 Antibody (8B7) - BSA Free

  • cancer/testis antigen 106
  • CDCA1hsNuf2
  • cell division cycle associated 1
  • Cell division cycle-associated protein 1
  • CT106
  • hNuf2
  • kinetochore protein Nuf2
  • NUF2, NDC80 kinetochore complex component, homolog (S. cerevisiae)
  • NUF2RhNuf2R

Background

Nuf2, also known as Kinetochore protein Nuf2, is a 54 kDa 464 amino acid protein, and it is involved in chromosome segregation, specifically as it relates to spindle checkpoint activity with the kinetochore-associated NDC80 complex. This protein is necessary for kinetochore stability and organization of microtubule binding sites on the outer plate, forming interactions with NDC80/HEC-1-CDCA1, SPBC24-SPBC25, Bub1, EXOC1, as well as AURKB/Aurora-B and CENPE in the mitotic prometaphase, DNA replication, and Cell Cycle pathways. Current research is being performed on this proteins involvement in gastric, lung, and breast cancers, in addition to essential hypertension, schizophrenia, and duodenogastric reflux.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Bioinformatics

Gene Symbol NUF2