NTS1/NTSR1 Antibody - BSA Free

Immunohistochemistry-Paraffin: Neurotensin Receptor 1 Antibody [NLS938] - Human Bladder, Carcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

Immunohistochemistry-Paraffin: Neurotensin Receptor 1 Antibody [NLS938] - Analysis of anti-NTSR1 / NTR antibody with brain, neurons and glia at 16 ug/ ml.

Immunohistochemistry-Paraffin: Neurotensin Receptor 1 Antibody [NLS938] - Analysis of anti-NTSR1 / NTR antibody with human adrenal, pheochromocytoma.

Immunohistochemistry-Paraffin: Neurotensin Receptor 1 Antibody [NLS938] - Human Ovary, Carcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

Immunohistochemistry-Paraffin: Neurotensin Receptor 1 Antibody [NLS938] - Human Lung, Adenocarcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

• Reactivity: Hu, Pm
• Applications: IHC
• Clonality: Polyclonal
• Host: Rabbit
• Conjugate: Unconjugated
• Format: BSA Free
• Concentration: 0.6 mg/ml

NTS1/NTSR1 Antibody - BSA Free Summary

• Description: Product can be stored undiluted at 4C for up to 1 month.
• Immunogen: Synthetic 17 amino acid peptide from 3rd cytoplasmic domain of human NTS1/NTSR1.
• Epitope: 3rd cytoplasmic domain
• Specificity: Human NTSR1. BLAST analysis of the peptide immunogen showed no homology with other human proteins.
• Predicted Species: Primate (100%). Backed by our 100% Guarantee.
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: NTSR1
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • Immunohistochemistry
  • Immunohistochemistry-Paraffin 16 ug/ml
• Application Notes: .

Reactivity Notes

Predicted cross-reactivity based on sequence identity: Gorilla (100%), Marmoset (88%), Canine (88%), Equine (88%).

Packaging, Storage & Formulations

• Storage: Keep as concentrated solution. Aliquot and store at -20C or below. Avoid multiple freeze-thaw cycles.
• Buffer: PBS
• Preservative: 0.1% Sodium Azide
• Concentration: 0.6 mg/ml
• Purity: Immunogen affinity purified

Alternate Names for NTS1/NTSR1 Antibody - BSA Free

• NTR
• NTR1
• NTRH
• NTRR
• NTS1
• NTSR1

Background

NTR1, a Neurotensin Receptor, activates a phosphatidylinositol-calcium second messenger system in the central and peripheral nervous systems. It mediates the functions of neurotensin, such as hypotension, hyperglycemia, hypothermia, antinociception, and regulation of intestinal motility and secretion. Neurotensin Receptor 1 expression is enhanced in pancreatic cancer and in chronic pancreatitis (Wang et al, 2000). Two differentially glycosylated forms of the NT1 receptor have been identified in rats, a 54-kDa form that is expressed from birth to adulthood, and a 52-kDa form only detected at 10 and 15 days postnatal. NTR1 has been reported in brain, pancreas, and small intestine. ESTs have been isolated from brain and colon libraries.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Publications for NTS1/NTSR1 Antibody (NLS938)(1)

Publication using NLS938

• Gui X, Liu S, Yan Y, Gao Z. Neurotensin receptor 1 overexpression in inflammatory bowel diseases and colitis-associated neoplasia World J Gastroenterol. 2013-07-28 [PMID: 23901225] (IHC-P, Human)

Review for NTS1/NTSR1 Antibody (NLS938) (1)

Average Rating: 3

(Based on 1 review)

We have 1 review tested in 1 species: Human.

reviewed by: Verified Customer IHC-P Human 12/29/2014

Summary

• Application: Immunohistochemistry-Paraffin
• Sample Tested: See PMID 23901225
• Species: Human

Bioinformatics

• Gene Symbol: NTSR1
• Entrez:
  • 4923(Human)
• Uniprot:
  • P30989(Human)