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Nox4 Peptide


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Product Details

Reactivity PmSpecies Glossary
Applications WB
1.0 mg/ml

Order Details

Nox4 Peptide Summary

A peptide to NOX4.
This peptide is specific for NB110-58851 only.
Protein/Peptide Type


  • Western Blot reported in scientific literature
Application Notes
This peptide is useful as a blocking peptide for NB110-58851. For further blocking peptide related protocol, click here.
Read Publication using
NB110-58851PEP in the following applications:

  • WB
    1 publication

Packaging, Storage & Formulations

Store at -80C. Avoid freeze-thaw cycles.
Peptide dissolved in dH2O. Contains no BSA.
No Preservative
1.0 mg/ml

Alternate Names for Nox4 Peptide

  • EC 1.6.3
  • Kidney oxidase-1
  • Kidney superoxide-producing NADPH oxidase
  • KOX
  • KOX-1
  • KOX-1Renal NAD(P)H-oxidase
  • NADPH oxidase 4
  • Nox4
  • RENOXEC 1.6.3.-


NOX4 (RENOX) is a renal gp91-phox homolog which functions in the kidney as an oxygen sensor and regulates the synthesis of erythropoietin. This protein is highly expressed at the site of erythropoietin production in the proximal convoluted tubule epithelial cells of the renal cortex.

NOX-4 is also expressed in fetal tissues, placenta, glioblastoma and vascular cells. Like gp91-phox, the enzymatic activity of NOX4 produces superoxide anions. In vascular cells, the addition of angiotensin II increases NOX4 expression, which indicates that NOX4 has a role in vascular oxidative stress response. NOX4 has a role as a redox messenger in the activation of intracellular signaling pathways leading (or contributing) to mitochondriogenesis, cell survival, and differentiation in hematopoietic stem cells. Data suggest that NOX4 provides a novel link between the insulin receptor and the generation of cellular reactive oxygen species that enhances insulin signal transduction.


This product is for research use only and is not approved for use in humans or in clinical diagnosis. Peptides and proteins are guaranteed for 3 months from date of receipt.

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Applications: IHC, KO, WB
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Applications: Flow, ICC/IF, IHC, IHC-P, PEP-ELISA, WB
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Applications: ELISA

Publications for Nox4 Peptide (NB110-58851PEP)(1)

We have publications tested in 1 confirmed species: Primate.

We have publications tested in 1 application: WB.

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Product General Protocols

Find general support by application which include: protocols, troubleshooting, illustrated assays, videos and webinars.

Video Protocols

WB Video Protocol

FAQs for Nox4 Peptide (NB110-58851PEP) (0)

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Additional Nox4 Products

Research Areas for Nox4 Peptide (NB110-58851PEP)

Find related products by research area.

Blogs on Nox4.

NOX4 Antibodies: Don't NOX them until you've tried them
NOX4 is an NADPH oxidase that generates superoxide within the cell. It is primarily found in vascular cells, fibroblasts, and osteoclasts, with abundant expression in the kidney. Unlike its family members NOX1 and NOX2, NOX4 is constitutively active, ...  Read full blog post.

NOX4 Antibodies in Diabetic Nephropathy Research
Diabetic nephropathy (DN) is one of the leading complications resulting from chronic diabetes. It manifests as progressive renal failure caused by mesangial cell hyperplasia and fibrosis, and is one of the leading causes of terminal kidney disease (1)...  Read full blog post.

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Gene Symbol NOX4