NLRP7 Antibody - BSA Free

Western Blot: NLRP7 Antibody [NBP2-19548] - Sample (30 ug of whole cell lysate) A: Jurkat 7. 5% SDS PAGE gel, diluted at 1:1000.

• Reactivity: Hu, Sh
• Applications: WB, ICC/IF, IHC
• Clonality: Polyclonal
• Host: Rabbit
• Conjugate: Unconjugated
• Format: BSA Free

NLRP7 Antibody - BSA Free Summary

• Description: Novus Biologicals Rabbit NLRP7 Antibody - BSA Free (NBP2-19548) is a polyclonal antibody validated for use in IHC, WB and ICC/IF. All Novus Biologicals antibodies are covered by our 100% guarantee.
• Immunogen: Recombinant protein encompassing a sequence within the center region of human NLRP7. The exact sequence is proprietary.
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: NLRP7
• Purity: Antigen Affinity-purified

Applications/Dilutions

• Dilutions:
  • Immunocytochemistry/ Immunofluorescence 1:10 - 1:500
  • Immunohistochemistry-Paraffin
  • Western Blot 1:500-1:3000
• Theoretical MW: 112 kDa.
  Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Reactivity Notes

Rhesus Monkey (87%).

Packaging, Storage & Formulations

• Storage: Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
• Buffer: 0.1M Tris, 0.1M Glycine, 20% Glycerol
• Preservative: 0.01% Thimerosal
• Purity: Antigen Affinity-purified

Alternate Names for NLRP7 Antibody - BSA Free

• CLR19.4
• MGC126471
• NACHT, leucine rich repeat and PYD containing 7
• NACHT, LRR and PYD containing protein 7
• NACHT, LRR and PYD domains-containing protein 7
• NALP7
• NALP7MGC126470
• NLR family, pyrin domain containing 7
• NLRP7
• NOD12
• NOD12HYDM
• Nucleotide-binding oligomerization domain protein 12
• nucleotide-binding oligomerization domain, leucine rich repeat and pyrin domaincontaining 7
• PAN7
• PYPAF3
• PYPAF3FLJ94610
• PYRIN-containing APAF1-like protein 3

Background

This gene encodes a member of the NACHT, leucine rich repeat, and PYD containing (NLRP) protein family. It has an N-terminal pyrin domain, followed by a NACHT domain, a NACHT-associated domain (NAD), and a C-terminal leucine-rich repeat (LRR) region. NLRP proteins are implicated in the activation of proinflammatory caspases through multiprotein complexes called inflammasomes. This gene may act as a feedback regulator of caspase-1-dependent interleukin 1-beta secretion. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq]

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause reproductive toxicity with developmental effects.  For more information go to www.P65Warnings.ca.gov.

Bioinformatics

• Gene Symbol: NLRP7
• Uniprot:
  • Q8WX94(Human)