NKG2D/CD314 Antibody (1D11) [DyLight 488]

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Product Details

Summary
Reactivity HuSpecies Glossary
Applications Flow, IHC-Fr, IHC-P
Clone
1D11
Clonality
Monoclonal
Host
Mouse
Conjugate
DyLight 488

NKG2D/CD314 Antibody (1D11) [DyLight 488] Summary

Immunogen
NKL cells.
Specificity
NB100-65956 is specific for CD314, also known as natural killer receptor G2 (NKG2D) and as killer cell lectin-like receptor subfamily K, member 1 (KLRK1). CD314 is a C-type lectin-like activating receptor which is expressed on most natural killer (NK) cells, CD8 T cells and gamma delta T cells. CD314 forms homodimers that signal through an associated DAP10 adaptor protein. Ligands of CD314 include MICA, MICB and UL16 binding protein (ULBP), which are inducibly expressed. Ligand binding to CD314 results in NK cell activation and potent costimulation of effector T cells. Clone 1D11 is reported to inhibit T cell recognition of MICA (1,6).
Isotype
IgG1
Clonality
Monoclonal
Host
Mouse
Gene
KLRK1
Purity
Protein G purified
Innovator's Reward
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Applications/Dilutions

Dilutions
  • Flow Cytometry
  • Immunohistochemistry-Frozen
  • Immunohistochemistry-Paraffin

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Purity
Protein G purified

Notes

Dylight (R) is a trademark of Thermo Fisher Scientific Inc. and its subsidiaries. This conjugate is made on demand. Actual recovery may vary from the stated volume of this product. The volume will be greater than or equal to the unit size stated on the datasheet.

Alternate Names for NKG2D/CD314 Antibody (1D11) [DyLight 488]

  • CD314 antigen
  • CD314
  • D12S2489E
  • FLJ17759
  • FLJ75772
  • Killer cell lectin-like receptor subfamily K member 1
  • killer cell lectin-like receptor subfamily K, member 1
  • KLR
  • KLRK1
  • NK cell receptor D
  • NKG2-D type II integral membrane protein
  • NKG2D
  • NKG2-D
  • NKG2-D-activating NK receptor
  • NKG2DDNA segment on chromosome 12 (unique) 2489 expressed sequence

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Secondary Antibodies

 

Isotype Controls

Other Available Formats

Allophycocyanin Labeled NB100-65956APC
DyLight 350 Labeled NB100-65956UV
DyLight 405 Labeled NB100-65956V
DyLight 680 Labeled NB100-65956FR
DyLight 755 Labeled NB100-65956IR
PE Labeled NB100-65956PE
PerCP Labeled NB100-65956PCP

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Bioinformatics Tool for NKG2D/CD314 Antibody (NB100-65956G)

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Diseases for NKG2D/CD314 Antibody (NB100-65956G)

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Bioinformatics

Gene Symbol KLRK1
Entrez