Nicotinamide N-Methyltransferase/NNMT Antibody (954208) [Alexa Fluor® 647]

• Reactivity: Hu
• Applications: WB
• Clone: 954208
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: Alexa Fluor 647

Nicotinamide N-Methyltransferase/NNMT Antibody (954208) [Alexa Fluor® 647] Summary

• Immunogen: E.coli-derived recombinant human Nicotinamide N‑Methyltransferase/NNMT
  Met1-Leu264
  Accession # P40261
• Specificity: Detects human Nicotinamide N‑Methyltransferase/NNMT in direct ELISAs and Western blots.
• Isotype: IgG2b
• Clonality: Monoclonal
• Host: Mouse
• Purity Statement: Protein A or G purified

Applications/Dilutions

• Dilutions:
  • Western Blot

Packaging, Storage & Formulations

• Storage: Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied
• Buffer: Supplied 0.2mg/ml in 1X PBS with RDF1 and 0.09% Sodium Azide

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for Nicotinamide N-Methyltransferase/NNMT Antibody (954208) [Alexa Fluor® 647]

• EC 2.1.1.1
• Nicotinamide NMethyltransferase
• Nicotinamide N-Methyltransferase
• NNMT

Background

Nicotinamide N-methyltransferase (NNMT) is a 264 aminoacids enzyme that catalyzes the N-methylation of nicotinamide and other pyridines to form pyridinium ions. This activity is important for biotransformation of many drugs and xenobiotic compounds. NNMT is found in human fat cells and the liver.  Significant up-regulation of NNMT was found pathologies like Parkinson's disease, cancer, atherosclerosis, and liver diseases.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.