NHE8 Antibody (7A11) [DyLight 488]

• Reactivity: Hu, Mu, Rt
• Applications: WB, ICC/IF
• Clone: 7A11
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: DyLight 488

NHE8 Antibody (7A11) [DyLight 488] Summary

• Immunogen: A fusion protein containing the C-terminal 89 residues of human NHE8. [Swiss-Prot# Q9Y2E8]
• Localization: Golgi apparatus membrane; multi-pass membrane.
• Specificity: This is specific for the 85 kDa mature glycosylated form of the protein. It does not recognize the 55 kDa immature form.
• Isotype: IgG
• Clonality: Monoclonal
• Host: Mouse
• Gene: SLC9A8
• Purity: Protein G purified

Applications/Dilutions

• Dilutions:
  • Immunocytochemistry/Immunofluorescence
  • Western Blot
• Application Notes: Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

• Storage: Store at 4C in the dark.
• Buffer: 50mM Sodium Borate
• Preservative: 0.05% Sodium Azide
• Purity: Protein G purified

Notes

DyLight (R) is a trademark of Thermo Fisher Scientific Inc. and its subsidiaries.

Alternate Names for NHE8 Antibody (7A11) [DyLight 488]

• DKFZp686C03237
• KIAA0939
• KIAA0939DKFZp686C03237
• MGC138418
• Na(+)/H(+) exchanger 8
• NHE8
• NHE-8
• NHE8FLJ42500
• SLC9A8
• sodium/hydrogen exchanger 8
• solute carrier family 9 (sodium/hydrogen exchanger)
• solute carrier family 9 (sodium/hydrogen exchanger), isoform 8
• solute carrier family 9 (sodium/hydrogen exchanger), member 8
• Solute carrier family 9 member 8

Background

Sodium-Hydrogen ion Exchangers (NHEs) are a growing family of transmembrane proteins. NHE8 is expressed in the kidney, where it may contribute to apical membrane ion transport physiology. It is highly expressed in the proximal tubules in the outer stripe of the outer medulla with significant but lower expression in the proximal tubules in the cortex.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: SLC9A8