Somatostatin R2/SSTR2 Antibody

Images

 
Immunohistochemistry-Paraffin: Somatostatin Receptor 2 Antibody [NB300-157] - IHC staining of Somatostatin Receptor 2 in mouse pancreas using DAB with hematoxylin counterstain.
Immunohistochemistry-Paraffin: Somatostatin Receptor 2 Antibody [NB300-157] - Staining of paraffin embedded rat tissue.

Product Details

Summary
Reactivity Hu, Mu, RtSpecies Glossary
Applications WB, Flow, ICC/IF, IHC, IHC-Fr, IHC-P, IP
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated

Order Details

Somatostatin R2/SSTR2 Antibody Summary

Immunogen
A synthetic peptide made to the C-terminus of rat Somatostatin Receptor 2 [UniProt# P30680]
Localization
Cell Membrane
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
SSTR2
Purity
Unpurified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Western Blot 1:100-1:1000
  • Flow Cytometry
  • Immunocytochemistry/Immunofluorescence 1:100 -1:250
  • Immunohistochemistry 1:100
  • Immunohistochemistry-Frozen 1:100
  • Immunohistochemistry-Paraffin 1:100
  • Immunoprecipitation 1:10-1:500
Application Notes
This Somatostatin Receptor 2 antibody is useful for Western blot, Immunoprecipitation, Immunocytochemistry/Immunofluorescence and Immunohistochemistry on paraffin-embedded and frozen sections. Flow Cytometry was reported in scientific literature. In WB, a band can be seen at 75-85 kDa. Multiple smaller MW bands may be seen as well.
Control Peptide
Somatostatin R2/SSTR2 Peptide (NB300-157PEP)
Publications
Read Publications using
NB300-157 in the following applications:

Packaging, Storage & Formulations

Storage
Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
Buffer
Whole antisera
Preservative
0.05% Sodium Azide
Purity
Unpurified

Notes

Licensed to Novus Biologicals LLC under U.S. Patent No 5,998,154.

Alternate Names for Somatostatin R2/SSTR2 Antibody

  • Smstr2
  • Somatostatin R2
  • somatostatin receptor 2
  • somatostatin receptor type 2
  • SomatostatinR2
  • SRIF-1
  • SS2R
  • SS-2-R
  • SS2-R
  • SST2
  • SSTR2

Background

Somatostatin is a tetradecapeptide that is widely distributed in the body. It acts on multiple organs in the body and also functions as a neuropeptide affecting electrical activity of neurons. Somatostatin Receptor 2 (SSR2), along with SSR1, is expressed at the highest levels in the stomach and jejunum, cerebrum and kidney, respectively.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Applications: WB, Flow, ICC/IF, IHC, IHC-Fr, IHC-P, IP

Publications for Somatostatin R2/SSTR2 Antibody (NB300-157)(6)

We have publications tested in 2 confirmed species: Human, Rat.

We have publications tested in 5 applications: FLOW, ICC/IF, IHC-Fr, IHC-P, WB.


Filter By Application
FLOW
(1)
ICC/IF
(1)
IHC-Fr
(2)
IHC-P
(2)
WB
(4)
All Applications
Filter By Species
Human
(2)
Rat
(2)
All Species
Showing Publications 1 - 6 of 6.
Publications using NB300-157 Applications Species
Wang Z, Ma W, Wang J et al. Imaging and therapy of hSSTR2-transfected tumors using radiolabeled somatostatin analogs. Tumour Biol 2013 Apr 19 [PMID: 23605323] (FLOW) FLOW
Li F, Ryu BY, Krueger RL et al. Targeted entry via somatostatin receptors using a novel modified retrovirus glycoprotein that delivers genes at levels comparable to wild type viral glycoproteins. Journal of Virology. 2011 Oct 19. [PMID: 22013043]
Reubi JC, Laissue JA, Waser B et al. Immunohistochemical detection of somatostatin sst2a receptors in the lymphatic, smooth muscular, and peripheral nervous systems of the human gastrointestinal tract: facts and artifacts. J Clin Endocrinol Metab;84(8):2942-50. 1999 Aug. [PMID: 10443702] (WB, IHC-P, IHC-Fr, Human) WB, IHC-P, IHC-Fr Human
Reubi JC, Kappeler A, Waser B et al. Immunohistochemical localization of somatostatin receptors sst2A in human tumors. Am J Pathol;153(1):233-45. 1998 Jul. [PMID: 9665484] (IHC-P, IHC-Fr, WB, Human) IHC-P, IHC-Fr, WB Human
Gu YZ, Schonbrunn A. Coupling specificity between somatostatin receptor sst2A and G proteins: isolation of the receptor-G protein complex with a receptor antibody. Mol Endocrinol;11(5):527-37. 1997 May. [PMID: 9139797] (WB, Rat) WB Rat
Dournaud P, Gu YZ, Schonbrunn A et al. Localization of the somatostatin receptor SST2A in rat brain using a specific anti-peptide antibody. J Neurosci;16(14):4468-78. 1996 Jul 15. [PMID: 8699257] (WB, ICC/IF, Rat) WB, ICC/IF Rat

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Product General Protocols

View specific protocols for Somatostatin R2/SSTR2 Antibody (NB300-157): Find general support by application which include: protocols, troubleshooting, illustrated assays, videos and webinars.

Video Protocols

WB Video Protocol
ICC/IF Video Protocol

FAQs for Somatostatin R2/SSTR2 Antibody (NB300-157). (Showing 1 - 1 of 1 FAQs).

  1. Is there any data to show that this antibody specifically detects sstr2 since it says that it is unpurified sera?
    • All of our current data for NB300-157 is available online. We have 6 available publications for this antibody as well. This product has been shown to specifically target the protein of interest by WB in published data. If you are interested in a blocking peptide to assist in your research, we do offer one specifically for this antibody - Somatostatin R2 SSTR2 Peptide (NB300-157PEP).

Secondary Antibodies

 

Isotype Controls

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Bioinformatics

Gene Symbol SSTR2
Entrez
Uniprot