NFAM1 Antibody (374301)

• Reactivity: Hu
• Applications: WB
• Clone: 374301
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: Unconjugated
• Concentration: LYOPH

NFAM1 Antibody (374301) Summary

• Immunogen: E. coli-derived recombinant human NFAM1
  Gln43-Lys163
  Accession # Q8NET5
• Specificity: Detects human NFAM1 in direct ELISAs and Western blots.
• Source: N/A
• Isotype: IgG2b
• Clonality: Monoclonal
• Host: Mouse
• Gene: NFAM1
• Purity Statement: Protein A or G purified from hybridoma culture supernatant

Applications/Dilutions

• Dilutions:
  • Western Blot 1 ug/mL

Packaging, Storage & Formulations

• Storage: Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
  • 12 months from date of receipt, -20 to -70 °C as supplied.
  • 1 month, 2 to 8 °C under sterile conditions after reconstitution.
  • 6 months, -20 to -70 °C under sterile conditions after reconstitution.
• Buffer: Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.
• Preservative: No Preservative
• Concentration: LYOPH
• Reconstitution Instructions: Reconstitute at 0.5 mg/mL in sterile PBS.

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for NFAM1 Antibody (374301)

• calcinerin/NFAT-activating ITAM-containing protein
• Calcineurin/NFAT-activating ITAM-containing protein
• CNAIP
• CNAIPbK126B4.4
• FLJ40652
• NFAM1
• NFAT activating protein with ITAM motif 1
• NFAT activation molecule 1
• NFAT-activating protein with ITAM motif 1

Background

NFAM1 is a ~30 kDa transmembrane ITAM-containing glycoprotein of the Ig superfamily that activates the NFAT family of transcription factors. NFAM1 is expressed in leukocytes, predominantly splenic B and T cells, and is involved in B cell activation and signaling. The 121 aa human NFAM1 extracellular domain contains one V‑type Ig-like domain and shows 45% aa identity with mouse NFAM1. The 86 aa cytoplasmic domain contains one ITAM consensus sequence.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: NFAM1
• Uniprot:
  • Q8NET5()