NF-L Antibody (NR-4) [DyLight 488]

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Product Details

Summary
Reactivity Hu, Rt, Po, Ch, PmSpecies Glossary
Applications Flow, IHC, IHC-P
Clone
NR-4
Clonality
Monoclonal
Host
Mouse
Conjugate
DyLight 488

Order Details

NF-L Antibody (NR-4) [DyLight 488] Summary

Immunogen
Crude neurofilament preparation from porcine spinal cord
Localization
Cytoplasmic
Marker
Neuronal Marker
Specificity
This MAb reacts with a 68kDa protein, identified as light sub-unit of neurofilaments (NF-L). Neurofilaments make up the main structural elements of axons and dendrites and are found in neurons, peripheral nerves, and sympathetic ganglion cells. Neurofilaments consist of three major subunits with molecular weights of 68kDa (NF-L), 160kDa (NF-M) and 200kDa (NF-H). Anti-neurofilament stains a number of neural, neuroendocrine, and endocrine tumors. Neuromas, ganglioneuromas, gangliogliomas, ganglioneuroblastomas, and neuroblastomas stain positively for anti-neurofilament. Neurofilaments are also present in paragangliomas as well as adrenal and extra-adrenal pheochromocytomas. Carcinoids, neuroendocrine carcinomas of the skin, and oat cell carcinomas of the lung also express neurofilament.
Isotype
IgG1
Clonality
Monoclonal
Host
Mouse
Gene
NEFL
Purity
Protein A or G purified
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Applications/Dilutions

Dilutions
  • Flow Cytometry
  • Immunohistochemistry
  • Immunohistochemistry-Paraffin
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Purity
Protein A or G purified

Notes

Dylight (R) is a trademark of Thermo Fisher Scientific Inc. and its subsidiaries. This conjugate is made on demand. Actual recovery may vary from the stated volume of this product. The volume will be greater than or equal to the unit size stated on the datasheet.

Alternate Names for NF-L Antibody (NR-4) [DyLight 488]

  • 68 kDa neurofilament protein
  • CMT2E
  • NEFL
  • neurofilament protein, light chain
  • neurofilament subunit NF-L
  • Neurofilament triplet L protein
  • neurofilament, light polypeptide
  • neurofilament-light
  • NF68
  • NF68FLJ53642
  • NFL
  • NF-L
  • NFLlight polypeptide 68kDa

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Secondary Antibodies

 

Isotype Controls

Other Available Formats

Alexa Fluor 350 NBP2-47969AF350
Alexa Fluor 405 NBP2-47969AF405
Alexa Fluor 488 NBP2-47969AF488
Alexa Fluor 532 NBP2-47969AF532
Alexa Fluor 594 NBP2-47969AF594
Alexa Fluor 647 NBP2-47969AF647
Alexa Fluor 700 NBP2-47969AF700
Alexa Fluor 750 NBP2-47969AF750
Allophycocyanin NBP2-47969APC
Biotin NBP2-47969B
DyLight 350 NBP2-47969UV
DyLight 405 NBP2-47969V
DyLight 488 NBP2-47969G
DyLight 550 NBP2-47969R
DyLight 594 NBP2-47969DL594
DyLight 650 NBP2-47969C
DyLight 680 NBP2-47969FR
DyLight 755 NBP2-47969IR
FITC NBP2-47969F
HRP NBP2-47969H
Janelia Fluor 549 NBP2-47969JF549
Janelia Fluor 646 NBP2-47969JF646
PE NBP2-47969PE
PerCP NBP2-47969PCP

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Bioinformatics Tool for NF-L Antibody (NBP2-47969G)

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Contact Information

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Calculators

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Bioinformatics

Gene Symbol NEFL