Species: Hu, Mu, Rt, Po, Bv
Applications: WB, ICC/IF, IHC, KO
Host: Rabbit Polyclonal
Species: Hu, Mu, Rt, Av, Bv, Ma
Applications: WB, Simple Western, ICC/IF, IHC
Host: Mouse Monoclonal
Species: Hu, Mu, Rt
Applications: WB, ICC/IF, IHC
Host: Mouse Monoclonal
Species: Hu
Applications: ELISA
Species: Mu
Applications: ELISA
Species: Hu
Applications: WB
Species: Hu
Applications: AC
Description
Neurofilaments are 10nm intermediate filament proteins located in vertebrate neurons, which regulate axonal diameter. They are composed predominantly of the three major neurofilament proteins: NF-Light, NF-Medium and NF-Heavy. NF-L is the light or low molecular weight polypeptide, and it runs on SDS-PAGE gels at about 68kDa, with some size variation in across species.
Antibodies to NF-L may be used to identify NF-L in neurons and to study neuronal processes in tissue sections and/or culture. NF-L antibodies can also be used to study microfilament accumulations seen in many neurological diseases, such as Lou Geri's disease or Alzheimer's disease.
Bioinformatics
| Product By Gene ID |
4747 |
| Alternate Names |
- 68 kDa neurofilament protein
- CMT2E
- NEFL
- neurofilament protein, light chain
- neurofilament subunit NF-L
- Neurofilament triplet L protein
- neurofilament, light polypeptide
- neurofilament-light
- NF68
- NF68FLJ53642
- NFL
- NF-L
- NFLlight polypeptide 68kDa
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