Neurturin Antibody

Western Blot: Neurturin Antibody [NBP1-06057] - (0.1ug/ml) staining of Human Heart lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.

Immunohistochemistry-Paraffin: Neurturin Antibody [NBP1-06057] - Staining of paraffin embedded Human Colon. Steamed antigen retrieval with citrate buffer pH 6, AP-staining. Primary antibody at 5 ug/ml.

• Reactivity: Hu, Mu
• Applications: WB, ELISA, IHC
• Clonality: Polyclonal
• Host: Goat
• Conjugate: Unconjugated
• Concentration: 0.5 mg/ml

Neurturin Antibody Summary

• Description: Novus Biologicals Goat Neurturin Antibody (NBP1-06057) is a polyclonal antibody validated for use in IHC, WB and ELISA. Anti-Neurturin Antibody: Cited in 1 publication. All Novus Biologicals antibodies are covered by our 100% guarantee.
• Immunogen: Peptide with sequence C-DAHSRYHTVHELSARE corresponding to C-Terminus according to NP_004549.1.
• Epitope: C-DAHSRYHTVHELSARE
• Isotype: IgG
• Clonality: Polyclonal
• Host: Goat
• Gene: NRTN
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • Immunohistochemistry
  • Immunohistochemistry-Paraffin 5 ug/ml
  • Peptide ELISA Detection limit 1:64000
  • Western Blot 0.1 - 0.3 ug/ml
• Application Notes: WB: Approx. 25 kDa band observed in human heart and mouse heart lysates (calculated MW of 22.4 kDa band according to NP_004549.1).

Packaging, Storage & Formulations

• Storage: Store at -20C. Avoid freeze-thaw cycles.
• Buffer: Tris saline (20 mM Tris pH 7.3, 150 mM NaCl), 0.5% BSA
• Preservative: 0.02% Sodium Azide
• Concentration: 0.5 mg/ml
• Purity: Immunogen affinity purified

Alternate Names for Neurturin Antibody

• Neurturin
• NRTN
• NTN

Background

Neurturin is a member of the TGF-beta subfamily, TRN. This gene signals through RET and a GPI-linked coreceptor, and promotes survival of neuronal populations. A neurturin mutation has been described in a family with Hirschsprung Disease. [provided by RefSeq]

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Publications for Neurturin Antibody (NBP1-06057)(1)

Publication using NBP1-06057

• Ye M, Wang XJ, Zhang YH et al. Transplantation of bone marrow stromal cells containing the neurturin gene in rat model of Parkinson's disease. Brain Res 2007-04-20 [PMID: 17336273]

Bioinformatics

• Gene Symbol: NRTN
• Entrez:
  • 4902(Human)
• Uniprot:
  • NP_004549.1(Human)