Neurturin Antibody (126422) [Alexa Fluor® 405]

• Reactivity: Hu
• Applications: WB, B/N
• Clone: 126422
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: Alexa Fluor 405

Neurturin Antibody (126422) [Alexa Fluor® 405] Summary

• Immunogen: E. coli-derived recombinant human Neurturin
  Ala96-Val197
  Accession # Q99748
• Specificity: Detects human Neurturin in direct ELISAs and Western blots. In direct ELISAs, approximately 80% cross-reactivity with recombinant mouse Neurturin is observed and no cross-reactivity with recombinant mouse (rm) Artemin, recombinant human (rh
• Isotype: IgG2b
• Clonality: Monoclonal
• Host: Mouse
• Purity Statement: Protein A or G purified

Applications/Dilutions

• Dilutions:
  • Blockade of Receptor-ligand Interaction
  • Western Blot

Packaging, Storage & Formulations

• Storage: Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied
• Buffer: Supplied 0.2mg/ml in 1X PBS with RDF1 and 0.09% Sodium Azide

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for Neurturin Antibody (126422) [Alexa Fluor® 405]

• Neurturin
• NRTN
• NTN

Background

Neurturin is a member of the GDNF family of ligands and is distantly related to TGF-beta family ligands. It is a disulfide-linked homodimer that interacts with a receptor complex composed of a high affinity ligand binding component (GFR alpha 1 or GFR alpha 2) and a common signaling component, cRET. Neurturin promotes the survival of a variety of neurons and possibly other cell types.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.