Neuronal Pentraxin 2 Antibody - BSA Free

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Western Blot: Neuronal Pentraxin 2 Antibody [NBP1-76899] - Independent Antibody Validation (IAV) via Protein Expression Profile in Cell Lines. Loading: 15 ug of lysates per lane. Antibodies: Neuronal Pentraxin 2 ...read more
Immunohistochemistry-Paraffin: Neuronal Pentraxin 2 Antibody [NBP1-76899] - Staining of NPTX2 in mouse brain tissue with NPTX2 antibody at 5 ug/ml.
Western Blot: Neuronal Pentraxin 2 Antibody [NBP1-76899] - Mouse brain tissue lysate with NPTX2 antibody at (A) 0.5 and (B) 1 ug/mL.
Western Blot: Neuronal Pentraxin 2 Antibody [NBP1-76899] - Mouse brain tissue lysate with NPTX2 antibody at 1 ug/ml in (A) the absence and (B) the presence of blocking peptide.
Immunohistochemistry-Paraffin: Neuronal Pentraxin 2 Antibody [NBP1-76899] - Human brain with NPTX2 antibody at 5 ug/ml.
Immunofluorescence: Neuronal Pentraxin 2 Antibody [NBP1-76899] - Mouse brain tissue with NPTX2 antibody at 20 ug/mL. Red: NPTX2 Antibody Blue: DAPI staining
Immunofluorescence: Neuronal Pentraxin 2 Antibody [NBP1-76899] - Immunofluorescence of NPTX2 in Human Brain cells with NPTX2 antibody at 20 ug/mL.

Product Details

Summary
Reactivity Hu, Mu, RtSpecies Glossary
Applications WB, ELISA, IHC, IHC-P, ICC/IF
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated
Format
BSA Free
Concentration
1 mg/ml

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Catalog# & Formulation Size Price

Neuronal Pentraxin 2 Antibody - BSA Free Summary

Immunogen
Antibody was raised against a 16 amino acid synthetic peptide near the center of the human NPTX2. The immunogen is located within amino acids 170 - 220 of NPTX2. Amino Acid Squence: LHNETSAHRQKTESTL
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
NPTX2
Purity
Peptide affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • ELISA 1:100-1:2000
  • Immunofluorescence 20 ug/ml
  • Immunohistochemistry 1:10-1:500
  • Immunohistochemistry-Paraffin 1:10-1:500
  • Western Blot
Theoretical MW
47 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.
Control Peptide
Neuronal Pentraxin 2 Peptide (NBP1-76899PEP)

Reactivity Notes

Immunogen displays the following percentage of sequence identity for non-tested species: Guinea pig (88%)

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS
Preservative
0.02% Sodium Azide
Concentration
1 mg/ml
Purity
Peptide affinity purified

Alternate Names for Neuronal Pentraxin 2 Antibody - BSA Free

  • Apexin
  • NARP
  • neuronal activity-regulated pentaxin
  • Neuronal Pentraxin 2
  • neuronal pentraxin IIapexin
  • neuronal pentraxin-2
  • NP2
  • NP-II
  • NPTX2

Background

Neuronal pentraxin (NPTX) 2 was initially identified as a member of the pentraxin family having high homology to NPTX1. Unlike NPTX1 however, NPTX2 is expressed in testes, pancreas, liver, heart, skeletal muscle as well as brain. NPTX2 possesses the lectin properties common to the pentraxin family, promotes neurite outgrowth, and is rapidly regulated by neuronal activity. NPTX1 and NPTX2 form heterocomplexes that contribute to both activity-independent and -dependent excitatory synaptogenesis. Recently, NPTX2 has been found to be highly upregulated in Parkinsonian substantia nigra and localizes to Lewy bodies and Lewy neurites in sporadic Parkinson's disease (PD), suggesting that it is involved in the pathway dysregulation that underlies PD. This NPTX2 antibody is predicted to be specific to NPTX2 and not recognize NPTX1.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Secondary Antibodies

 

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Bioinformatics

Gene Symbol NPTX2
Uniprot