Neurogenin-3 Antibody

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Immunohistochemistry-Paraffin: Neurogenin-3 Antibody [NBP2-27115] - Analysis of Neurogenin3 in FFPE mouse pancreas tissue using NBP2-27115 at 5 ug/ml.

Product Details

Summary
Reactivity MuSpecies Glossary
Applications IHC, IHC-P
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated
Concentration
1.0 mg/ml

Order Details

Neurogenin-3 Antibody Summary

Immunogen
A portion of amino acids 1-69 of mouse Neurog 3 was used as the immunogen.
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
NEUROG3
Purity
Immunogen affinity purified
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Applications/Dilutions

Dilutions
  • Immunohistochemistry
  • Immunohistochemistry-Paraffin 5ug/ml

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS
Preservative
0.05% Sodium Azide
Concentration
1.0 mg/ml
Purity
Immunogen affinity purified

Alternate Names for Neurogenin-3 Antibody

  • Atoh5
  • BHLHA7
  • bHLHa7NGN-3
  • Class A basic helix-loop-helix protein 7
  • Math4B
  • NEUROG3
  • neurogenin 3
  • Neurogenin3
  • Neurogenin-3
  • NGN3
  • Protein atonal homolog 5
  • Relax

Background

Neurog 3 protein contains one basic helix-loop-helix (bHLH) domain. It is both necessary and sufficient to induce endocrine islet cell differentiation from embryonic pancreatic progenitors. Not only does it initiates endocrine cell differentiation, it also promotes islet cell maturation and maintains islet function. It is reported that Neurogenin 3 can redirect the differentiation of bipotential secretory progenitors to endocrine rather than goblet cell fate.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Secondary Antibodies

 

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Bioinformatics

Gene Symbol NEUROG3
Entrez