N-Acetylgalactosamine-6-Sulfatase/GALNS Antibody - BSA Free

Immunohistochemistry-Paraffin: N-Acetylgalactosamine-6-Sulfatase/GALNS Antibody [NBP3-17895] - Staining of human testis shows moderate cytoplasmic positivity in cells in seminiferous ducts and Leydig cells.

• Reactivity: Hu
• Applications: IHC
• Clonality: Polyclonal
• Host: Rabbit
• Conjugate: Unconjugated
• Format: BSA Free

N-Acetylgalactosamine-6-Sulfatase/GALNS Antibody - BSA Free Summary

• Description: Novus Biologicals Rabbit N-Acetylgalactosamine-6-Sulfatase/GALNS Antibody - BSA Free (NBP3-17895) is a polyclonal antibody validated for use in IHC. All Novus Biologicals antibodies are covered by our 100% guarantee.
• Immunogen: This antibody was developed against Recombinant Protein corresponding to amino acids: ALDFIKRQARHHPFFLYWAVDATHAPVYASKPFLGTSQRGRYGDAVREIDDSIGKILELLQDLHVADNTFVFFTSDNGAALISAPEQGGSNGPFLCGKQT
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: GALNS
• Purity: Affinity purified

Applications/Dilutions

• Dilutions:
  • Immunohistochemistry 1:20 - 1:50
  • Immunohistochemistry-Paraffin 1:20 - 1:50
• Application Notes: For IHC-Paraffin, HIER pH 6 retrieval is recommended.

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: PBS, pH 7.2, 40% glycerol
• Preservative: 0.02% Sodium Azide
• Purity: Affinity purified

Alternate Names for N-Acetylgalactosamine-6-Sulfatase/GALNS Antibody - BSA Free

• Chondroitinase
• Chondroitinsulfatase
• EC 3.1.6
• EC 3.1.6.4
• FLJ17434
• FLJ42844
• FLJ98217
• GA6S
• galactosamine (N-acetyl)-6-sulfate sulfatase
• Galactose-6-Sulfate Sulfatase
• GalNAc6S Sulfatase
• GALNAC6S
• GALNS
• GAS
• MPS4A
• NAcetylgalactosamine6Sulfatase
• N-Acetylgalactosamine-6-Sulfatase
• N-acetylgalactosamine-6-sulfate sulfatase

Background

GALNS encodes N-acetylgalactosamine-6-sulfatase which is a lysosomal exohydrolase required for the degradation of the glycosaminoglycans, keratan sulfate, and chondroitin 6-sulfate. Sequence alterations including point, missense and nonsense mutations, as well as those that affect splicing, result in a deficiency of this enzyme. Deficiencies of this enzyme lead to Morquio A syndrome, a lysosomal storage disorder. [provided by RefSeq]

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: GALNS