Myosin Heavy Chain Antibody (MF20) [Fluorescein]

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Three-day differentiated C2C12 mouse myoblast cell line was stained with Mouse Anti-Human Myosin Heavy Chain Fluorescein‑conjugated Monoclonal Antibody (Catalog # IC4470F, filled histogram) or isotype control antibody ...read more

Product Details

Summary
Reactivity HuSpecies Glossary
Applications Flow
Clone
MF20
Clonality
Monoclonal
Host
Mouse
Conjugate
Fluorescein

Order Details

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Catalog# & Conjugate Size Price
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Myosin Heavy Chain Antibody (MF20) [Fluorescein] Summary

Immunogen
Chicken pectoralis-derived Myosin
Specificity
Detects Myosin Heavy Chain in human, mouse, rat and other mammalian, avian, and amphibian species.
Source
N/A
Isotype
IgG2b
Clonality
Monoclonal
Host
Mouse
Gene
MYH14
Purity Statement
Protein A or G purified from hybridoma culture supernatant
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Intracellular Staining by Flow Cytometry 10 uL/10^6 cells
Publications
Read Publications using
IC4470F in the following applications:

Packaging, Storage & Formulations

Storage
Store the unopened product at 2 - 8° C. Do not use past expiration date. Protect from light.
Buffer
Supplied in a saline solution containing BSA and Sodium Azide.
Preservative
Sodium Azide

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for Myosin Heavy Chain Antibody (MF20) [Fluorescein]

  • DFNA4
  • FLJ13881
  • FLJ43092
  • KIAA2034DKFZp667A1311
  • MHC16
  • MYH14 variant protein
  • MYH17
  • MYHC
  • Myosin heavy chain 14
  • Myosin Heavy Chain
  • Myosin heavy chain, non-muscle IIc
  • myosin
  • myosin, heavy chain 14
  • myosin, heavy chain 14, non-muscle
  • myosin, heavy polypeptide 14
  • myosin-14
  • NMHC II-C
  • NMHC-II-C
  • Non-muscle myosin heavy chain IIc
  • nonmuscle myosin heavy chain II-C

Background

Skeletal muscle Myosin or myosin II is the motor protein that generates force to drive muscle contraction. It is a 520 kDa hexamer comprised of two heavy chains and four light chains. Myosin heavy chain is 220 kDa in size and consists of a long coiled-coil domain tail that mediates dimerization of the two heavy chains and a globular head region that mediates ATP-dependent sliding of actin filaments. Myosin heavy chain can be proteolytically cleaved to produce heavy meromyosin, which includes the S1 motor domain (head region) and first third of the coiled coil domain, and light meromyosin, which includes the C-terminal two thirds of the coiled coil domain.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Publications for Myosin Heavy Chain Antibody (IC4470F)(5)

We have publications tested in 2 confirmed species: Human, Mouse.

We have publications tested in 3 applications: ICC, IHC, IHC-Fr.


Filter By Application
ICC
(3)
IHC
(1)
IHC-Fr
(1)
All Applications
Filter By Species
Human
(1)
Mouse
(4)
All Species
Showing Publications 1 - 5 of 5.
Publications using IC4470F Applications Species
K Awad, N Ahuja, M Fiedler, S Peper, Z Wang, P Aswath, M Brotto, V Varanasi Ionic Silicon Protects Oxidative Damage and Promotes Skeletal Muscle Cell Regeneration International Journal of Molecular Sciences, 2021;22(2):. 2021 [PMID: 33419056] (ICC, Mouse) ICC Mouse
C Mo, Z Wang, L Bonewald, M Brotto Multi-Staged Regulation of Lipid Signaling Mediators during Myogenesis by COX-1/2 Pathways Int J Mol Sci, 2019;20(18):. 2019 [PMID: 31487817] (ICC, Mouse) ICC Mouse
LR Fiedler, K Chapman, M Xie, E Maifoshie, M Jenkins, PA Golforoush, M Bellahcene, M Noseda, D Faust, A Jarvis, G Newton, MA Paiva, M Harada, DJ Stuckey, W Song, J Habib, P Narasimham, R Aqil, D Sanmugalin, R Yan, L Pavanello, M Sano, SC Wang, RD Sampson, S Kanayagana, GE Taffet, LH Michael, ML Entman, TH Tan, SE Harding, CMR Low, C Tralau-Ste, T Perrior, MD Schneider MAP4K4 Inhibition Promotes Survival of Human Stem Cell-Derived Cardiomyocytes and Reduces Infarct Size In�Vivo Cell Stem Cell, 2019;0(0):. 2019 [PMID: 30853557] (IHC, Mouse) IHC Mouse
H Ohtsubo, Y Sato, T Suzuki, W Mizunoya, M Nakamura, R Tatsumi, Y Ikeuchi APOBEC2 negatively regulates myoblast differentiation in muscle regeneration Int. J. Biochem. Cell Biol, 2017;85(0):91-101. 2017 [PMID: 28215905] (ICC, Mouse) ICC Mouse
I Toral-Ojed, G Aldanondo, J Lasa-Elgar, H Lasa-Ferná, R Fernández-, A López de M, A Vallejo-Il Calpain 3 deficiency affects SERCA expression and function in the skeletal muscle Expert Rev Mol Med, 2016;18(0):e7. 2016 [PMID: 27055500] (IHC-Fr, Human) IHC-Fr Human

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Bioinformatics

Gene Symbol MYH14