Myocilin Antibody (297817)

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Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB
Clone
297817
Clonality
Monoclonal
Host
Mouse
Conjugate
Unconjugated
Concentration
LYOPH

Order Details

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Catalog# & Formulation Size Price

Myocilin Antibody (297817) Summary

Immunogen
Mouse myeloma cell line NS0-derived recombinant human Myocilin
Arg33-Met504
Accession # Q99972
Specificity
Detects human Myocilin in direct ELISAs and Western blots. In direct ELISAs, 75% cross-reactivity with recombinant mouse Myocilin is observed.
Source
N/A
Isotype
IgG2b
Clonality
Monoclonal
Host
Mouse
Gene
MYOC
Purity
Protein A or G purified from hybridoma culture supernatant
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Western Blot 1 ug/mL
Reviewed Applications
Read 1 Review rated 5
using
MAB3446 in the following application:

Publications
Read Publications using
MAB3446 in the following applications:

  • IP
    1 publication
  • WB
    1 publication

Packaging, Storage & Formulations

Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
  • 12 months from date of receipt, -20 to -70 °C as supplied.
  • 1 month, 2 to 8 °C under sterile conditions after reconstitution.
  • 6 months, -20 to -70 °C under sterile conditions after reconstitution.
Buffer
Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied as a 0.2 µm filtered solution in PBS.
Preservative
No Preservative
Concentration
LYOPH
Purity
Protein A or G purified from hybridoma culture supernatant
Reconstitution Instructions
Reconstitute at 0.5 mg/mL in sterile PBS.

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for Myocilin Antibody (297817)

  • GLC1A
  • GLC1Amyocilin
  • GPOA
  • JOAG
  • JOAG1
  • MYOC
  • Myocilin
  • myocilin, trabecular meshwork inducible glucocorticoid response
  • TIGR
  • TIGRmutated trabecular meshwork-induced glucocorticoid response protein
  • Trabecular meshwork-induced glucocorticoid response protein

Background

Myocilin (also known as TIGR) is a variably glycosylated, 65 kDa, secreted polypeptide that belongs to the family of olfactomedin-related proteins. Human Myocilin is synthesized as a 490 aa precursor that contains an 18 aa signal sequence, an 84 aa N-terminus, a 53 aa alpha ‑helical leucine zipper and a 335 aa C-terminus that contains a 260 aa OLF-domain. An alternate start site generates a signal-sequenceless 504 aa mature protein. Myocilin forms nondisulfide-linked dimers and multimers. The human 32 kDa OLF-domain shares 87% aa sequence identity with the OLF-domain in bovine, rat, and mouse.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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MAB3446
Species: Hu
Applications: WB

Publications for Myocilin Antibody (MAB3446)(2)

Review for Myocilin Antibody (MAB3446) (1) 51

Average Rating: 5
(Based on 1 review)
We have 1 review tested in 1 species: Pig.

Reviews using MAB3446:
Filter by Applications
ICC
(1)
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Pig
(1)
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Images Ratings Applications Species Date Details
Immunocytochemistry Myocilin MAB3446
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reviewed by:
Anonymous
ICC Pig 01/04/2017
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Summary

ApplicationImmunocytochemistry
Sample TestedPig TM cells
SpeciesPig

Comments

CommentsIHC showing detection of Myocilin using anti-Myocilin antibody (MAB3446) at 1:1000 dilution in Pig TM cells.

Product General Protocols

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Video Protocols

WB Video Protocol

FAQs for Myocilin Antibody (MAB3446) (0)

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Secondary Antibodies

 

Isotype Controls

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Bioinformatics Tool for Myocilin Antibody (MAB3446)

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Diseases for Myocilin Antibody (MAB3446)

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Pathways for Myocilin Antibody (MAB3446)

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PTMs for Myocilin Antibody (MAB3446)

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Blogs on Myocilin

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Recent Reviews

5
5
1
4
0
3
0
2
0
1
0

Anonymous
01/04/2017
Application: ICC
Species: Pig

Bioinformatics

Gene Symbol MYOC
Entrez
Uniprot