Myeloperoxidase/MPO Native Protein

Product Discontinued

Myeloperoxidase/MPO Native Protein Summary

• Description: Native Myeloperoxidase/MPO
  
  

  Source:Human Neutrophil
  Amino Acid Sequence:(P05164)

• Source: Human neutrophil
• Protein/Peptide Type: Native Protein
• Gene: MPO
• Purity: >95%, by SDS-PAGE

Applications/Dilutions

• Dilutions:
  • Bioactivity
  • SDS-Page
• Application Notes: Specific activity: 180-220 units per mg protein after lyophilization. One unit of activity is defined as the amount of enzyme that will decompose one micromole of hydrogen peroxide per minute at 25C , pH 6.1. Reaction mixture contains 33 mM sodium phosphate, pH 6.1, 30 mM guaiacol, and 0.0012% (0.35 mM) hydrogen peroxide
• Theoretical MW: 150 kDa.
  Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Packaging, Storage & Formulations

• Storage: Store at -20 to -80C. Avoid freeze-thaw cycles.
• Buffer: Lyophilized from 50 mM Na acetate (pH 6.0), 100 mM NaCl.
• Concentration: Lyoph
• Purity: >95%, by SDS-PAGE
• Reconstitution Instructions: Reconstitute with deionized H2O

Alternate Names for Myeloperoxidase/MPO Native Protein

• EC 1.11.1
• EC 1.11.1.7
• MPO
• Myeloperoxidase

Background

Myeloperoxidase (MPO) is a hemeprotein that belongs to the XPO subfamily of the heme peroxidase superfamily.This heme protein catalyzes oxidations by hydrogen peroxide, including MPO- chloride mediated killing of microbes and tumor cells, inactivation of hemotactic factors, crosslinking of proteins and inclination of proteins.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Peptides and proteins are guaranteed for 3 months from date of receipt.

Bioinformatics

• Gene Symbol: MPO