Musashi-1 Antibody

Product Discontinued

Musashi-1 Antibody Summary

• Immunogen: A portion of amino acids 200 to 250 of human Musashi-1 was used as immunogen.
• Marker: Neuronal Stem Cell Marker
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: MSI1
• Purity: Protein A purified

Applications/Dilutions

• Dilutions:
  • Western Blot 2-4 ug/ml

Reactivity Notes

The amino acid sequence used as immunogen is 100% homologous in human, mouse, rat, opossum, horse and cow, 93% homologous in chicken and Xenopus and 81% homologous in zebrafish.

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: 0.2 ml PBS and 0.05% BSA
• Preservative: 0.05% Sodium Azide
• Concentration: 0.5 mg/ml
• Purity: Protein A purified

Alternate Names for Musashi-1 Antibody

• MSI1
• Musashi (Drosophila) homolog 1
• musashi homolog 1 (Drosophila)
• Musashi1
• Musashi-1
• RNA-binding protein Musashi homolog 1

Background

Musashi1, a neural RNA-binding protein, plays an important role in regulating cell differentiation in precursor cells. Musashi-1 (Msi-1) has been shown to increase the accumulation of tau isoforms in intracellular inclusions in dementia. It may play a role in the pathogenesis of various neurodegenerative disorders. Musashi1 has also been detected in human tumor tissues such as gliomas and melanomas, suggesting its involvement in cancer development. Msi-1 also appears to play be an vital role in the development of several types of carcinoma such as human hepatoma, and may be a useful molecular marker for tumor detection.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: MSI1
• Uniprot:
  • O43347()