MTCH2 Antibody

Images

 
Western Blot: MTCH2 Antibody [NBP1-76998] - 293 cell lysate with MTCH2 antibody at 1 ug/mL.
Immunocytochemistry/ Immunofluorescence: MTCH2 Antibody [NBP1-76998] - Immunofluorescence of MTCH2 in Mouse Kidney cells with MTCH2 antibody at 20 ug/mL.
Immunohistochemistry-Paraffin: MTCH2 Antibody [NBP1-76998] - Mouse kidney tissue with MTCH2 antibody at 5 ug/ml.

Product Details

Summary
Reactivity Hu, MuSpecies Glossary
Applications WB, ELISA, ICC/IF, IHC, IHC-P
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated
Concentration
1 mg/ml

Order Details

MTCH2 Antibody Summary

Immunogen
Antibody was raised against a 15 amino acid synthetic peptide near the amino terminus of human MTCH2. The immunogen is located within amino acids 80 - 130 of MTCH2.
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
MTCH2
Purity
Immunogen affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Western Blot 1:100-1:2000
  • ELISA 1:100-1:2000
  • Immunocytochemistry/Immunofluorescence 20 ug/ml
  • Immunohistochemistry 1:10-1:500
  • Immunohistochemistry-Paraffin 1:10-1:500
Control Peptide
MTCH2 Peptide (NBP1-76998PEP)

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS
Preservative
0.02% Sodium Azide
Concentration
1 mg/ml
Purity
Immunogen affinity purified

Alternate Names for MTCH2 Antibody

  • 2310034D24Rik
  • Met-induced mitochondrial protein
  • MIMP
  • mitochondrial carrier 2
  • mitochondrial carrier homolog 2 (C. elegans)
  • mitochondrial carrier homolog 2

Background

Apoptosis plays a major role in normal organism development, tissue homeostasis, and removal of damaged cells. Disruption of this process has been implicated in a variety of diseases such as cancer. The Bcl-2 family of proteins is comprised of critical regulators of apoptosis that can be divided into two classes: those that inhibit apoptosis and those that promote cell death. MTCH2 is a member of the mitochondrial carrier protein family that catalyze the exchange of substrates across the inner mitochondrial membrane and is targeted by Bid, a pro-apoptotic Bcl-2 family member, in response to apoptotic signals, suggesting that MTCH2 may play a key role in the mitochondrial apoptosis pathway.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

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Video Protocols

WB Video Protocol
ICC/IF Video Protocol

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Secondary Antibodies

 

Isotype Controls

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Bioinformatics

Gene Symbol MTCH2
Uniprot