LZTR2 Antibody

Images

 
Western Blot: LZTR2 Antibody [NBP1-77122] - Mouse kidney tissue lysate with LZTR2 antibody at 1 ug/mL.
Immunocytochemistry/ Immunofluorescence: LZTR2 Antibody [NBP1-77122] - Mouse kidney tissue
Immunohistochemistry-Paraffin: LZTR2 Antibody [NBP1-77122] - Mouse kidney tissue with LZTR2 antibody at 5 ug/mL.

Product Details

Summary
Reactivity Hu, Mu, RtSpecies Glossary
Applications WB, ELISA, ICC/IF, IHC, IHC-P
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated
Concentration
1 mg/ml

Order Details

LZTR2 Antibody Summary

Immunogen
Antibody was raised against an 18 amino acid synthetic peptide near the carboxy terminus of human LZTR2. The immunogen is located within the last 50 amino acids of LZTR2.
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
SEC16B
Purity
Immunogen affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Western Blot 1:100-1:2000
  • ELISA 1:100-1:2000
  • Immunocytochemistry/Immunofluorescence 20 ug/mL
  • Immunohistochemistry 1:10-1:500
  • Immunohistochemistry-Paraffin 1:10-1:500
Control Peptide
LZTR2 Peptide (NBP1-77122PEP)

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS
Preservative
0.02% Sodium Azide
Concentration
1 mg/ml
Purity
Immunogen affinity purified

Alternate Names for LZTR2 Antibody

  • DKFZp686C2486
  • FLJ23871
  • FLJ25761
  • KIAA1928
  • Leucine zipper transcription regulator 2FLJ36620
  • LZTR2SEC16Sprotein SEC16 homolog B
  • PGPR-p117
  • protein transport protein Sec16B
  • Regucalcin gene promoter region-related protein p117
  • regucalcin gene promotor region related protein
  • RGPRFLJ33652
  • RGPR-p117
  • SEC16 homolog B (S. cerevisiae)
  • SEC16 homolog B

Background

LZTR2, also known as RGPR-p117, is a member of the BTB-kelch superfamily and was initially described as a nuclear factor I (NFI) binding protein and transcriptional regulator of the regucalcin gene. LZTR2 is cytoplasmically localized but is thought to translocate to the nucleus, a process mediated by protein kinase C signaling following hormonal stimulation. Recent evidence has suggested that there is a strong correlation of single nucleotide polymorphisms of LZTR2 with obesity in the Japanese population similar to that seen with the TMEM18 gene and the GNPDA2, BDNF, FAIM2, and MC4R genes with obesity in Caucasian populations, suggesting LZTR2 may play a role in metabolism and obesity risk.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

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Video Protocols

WB Video Protocol
ICC/IF Video Protocol

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Secondary Antibodies

 

Isotype Controls

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Bioinformatics

Gene Symbol SEC16B
Uniprot