MSPR/Ron Antibody (CL0463) - BSA Free

Western Blot: MSP R/Ron Antibody (CL0463) [NBP2-30924] - Lane 1: Marker [kDa]. Lane 2: Human cell line RT-4

Western Blot: MSP R/Ron Antibody (CL0463) [NBP2-30924] - Lane 1: Marker [kDa] 250, 130, 95, 72, 55, 36, 28, 17, 10. Lane 2: Negative control (vector only transfected HEK293T lysate). Lane 3: Over-expression lysate (Co-expressed with a C-terminal myc-DDK tag (3.1 kDa) in mammalian HEK293T cells).

• Reactivity: Hu
• Applications: WB
• Clone: CL0463
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: Unconjugated
• Format: BSA Free

MSPR/Ron Antibody (CL0463) - BSA Free Summary

• Description: Novus Biologicals Mouse MSPR/Ron Antibody (CL0463) - BSA Free (NBP2-30924) is a monoclonal antibody validated for use in WB. All Novus Biologicals antibodies are covered by our 100% guarantee.
• Immunogen: This antibody was developed using a recombinant protein derived from Q04912, with the exact immunogen sequence remaining proprietary.
• Isotype: IgG1
• Clonality: Monoclonal
• Host: Mouse
• Gene: MST1R
• Purity: Protein A purified

Applications/Dilutions

• Dilutions:
  • Western Blot 1 ug/ml
• Control Peptide:

  MSPR/Ron Recombinant Protein Antigen (NBP2-30924PEP)

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: PBS (pH 7.2) and 40% Glycerol
• Preservative: 0.02% Sodium Azide
• Purity: Protein A purified

Alternate Names for MSPR/Ron Antibody (CL0463) - BSA Free

• CD136 antigen
• CD136
• CDw136c-met-related tyrosine kinase
• EC 2.7.10
• EC 2.7.10.1
• macrophage stimulating 1 receptor (c-met-related tyrosine kinase)
• MSP R
• MSP receptor
• MSPR
• MST1R
• p185-Ron
• Protein-tyrosine kinase 8
• PTK8 protein tyrosine kinase 8
• PTK8
• Ron
• RONmacrophage-stimulating protein receptor
• soluble RON variant 1
• soluble RON variant 2
• soluble RON variant 3
• soluble RON variant 4

Background

Ron, the tyrosine kinase receptor for the Macrophage-stimulating protein, is involved in cell dissociation, motility, and matrix invasion (1). Ron, a cDNA homologous to the hepatocyte growth factor (HGF) receptor gene (MET), encodes a putative tyrosine kinase. It has been shown that the Ron gene is expressed in several epithelial tissues as well as in granulocytes and monocytes. The major RON transcript is translated into a glycosylated single chain precursor, cleaved into a 185 kDa heterodimer (p185Ron) of 35 (alpha) and 150 kDa (beta) disulfide-linked chains, before exposure at the cell surface (2).

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: MST1R
• Uniprot:
  • Q04912()