Species: Hu
Applications: WB
Host: Rabbit Polyclonal
Species: Hu
Applications: WB, IP, B/N
Host: Goat Polyclonal
Species: Hu
Applications: WB, Flow, ICC/IF, IHC, IP
Host: Rabbit Monoclonal
Species: Hu
Applications: ELISA
Species: Hu
Applications: WB
Species: Hu
Applications: Bioactivity
Species: Hu
Applications: Binding Activity
Species: Mu
Applications: Binding Activity
Description
Ron, the tyrosine kinase receptor for the Macrophage-stimulating protein, is involved in cell dissociation, motility, and matrix invasion (1). Ron, a cDNA homologous to the hepatocyte growth factor (HGF) receptor gene (MET), encodes a putative tyrosine kinase. It has been shown that the Ron gene is expressed in several epithelial tissues as well as in granulocytes and monocytes. The major RON transcript is translated into a glycosylated single chain precursor, cleaved into a 185 kDa heterodimer (p185Ron) of 35 (alpha) and 150 kDa (beta) disulfide-linked chains, before exposure at the cell surface (2).
Bioinformatics
Entrez |
Mouse Rat Human |
Uniprot |
Human Human |
Product By Gene ID |
4486 |
Alternate Names |
- CD136 antigen
- CD136
- CDw136c-met-related tyrosine kinase
- EC 2.7.10
- EC 2.7.10.1
- macrophage stimulating 1 receptor (c-met-related tyrosine kinase)
- MSP receptor
- p185-Ron
- Protein-tyrosine kinase 8
- PTK8 protein tyrosine kinase 8
- PTK8
- RONmacrophage-stimulating protein receptor
- soluble RON variant 1
- soluble RON variant 2
- soluble RON variant 3
- soluble RON variant 4
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