MSPR/Ron Products

Description

Ron, the tyrosine kinase receptor for the Macrophage-stimulating protein, is involved in cell dissociation, motility, and matrix invasion (1). Ron, a cDNA homologous to the hepatocyte growth factor (HGF) receptor gene (MET), encodes a putative tyrosine kinase. It has been shown that the Ron gene is expressed in several epithelial tissues as well as in granulocytes and monocytes. The major RON transcript is translated into a glycosylated single chain precursor, cleaved into a 185 kDa heterodimer (p185Ron) of 35 (alpha) and 150 kDa (beta) disulfide-linked chains, before exposure at the cell surface (2).

Bioinformatics

Entrez	19882 Mouse 300999 Rat 4486 Human
Uniprot	NP_002438 Human Q04912 Human
Product By Gene ID	4486
Alternate Names	CD136 antigen CD136 CDw136c-met-related tyrosine kinase EC 2.7.10 EC 2.7.10.1 macrophage stimulating 1 receptor (c-met-related tyrosine kinase) MSP receptor p185-Ron Protein-tyrosine kinase 8 PTK8 protein tyrosine kinase 8 PTK8 RONmacrophage-stimulating protein receptor soluble RON variant 1 soluble RON variant 2 soluble RON variant 3 soluble RON variant 4

Research Areas for MSPR/Ron

Find related products by research area and learn more about each of the different research areas below.

Apoptosis
Cell Cycle and Replication
GPCR
Immune System Diseases
Immunology
Phospho-Specific
Protein Kinase