MS4A3 Antibody (489433) [Alexa Fluor® 350]

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Product Details

Summary
Reactivity HuSpecies Glossary
Applications Flow
Clone
489433
Clonality
Monoclonal
Host
Mouse
Conjugate
Alexa Fluor 350
Concentration
Please see the vial label for concentration. If unlisted please contact technical services.

MS4A3 Antibody (489433) [Alexa Fluor® 350] Summary

Immunogen
NS0 mouse myeloma cell line transfected with human MS4A3
Accession # NP_006129
Specificity
Detects human MS4A3 in direct ELISAs.
Isotype
IgG2a
Clonality
Monoclonal
Host
Mouse
Gene
MS4A3
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Flow Cytometry 0.25-1 ug/10^6 cells
Application Notes
Flow Cytometry: Please use 0.25-1 ug of conjugated antibody per 10e6 cells.

Packaging, Storage & Formulations

Storage
Store the unopened product at 2 - 8 °C. Do not use past expiration date.
Buffer
Supplied 0.2 mg/mL in a saline solution containing BSA and Sodium Azide.
Preservative
0.09% Sodium Azide
Concentration
Please see the vial label for concentration. If unlisted please contact technical services.

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for MS4A3 Antibody (489433) [Alexa Fluor® 350]

  • CD20 antigen homolog
  • CD20 antigen-like protein
  • CD20L
  • CD20LIgE receptor beta subunit
  • hematopoietic cell 4 transmembrane protein
  • Hematopoietic-specific transmembrane protein 4
  • HTM4
  • HTM4IgE receptor beta chain
  • membrane-spanning 4-domains subfamily A member 3
  • membrane-spanning 4-domains, subfamily A, member 3 (hematopoieticcell-specific)
  • MS4A3

Background

MS4A3, also known as HTm4, is an intracytoplasmic membrane protein that is a member of the MS4A family of four-transmembrane proteins that also includes CD20 and Fc epsilon RI beta.  It is a cell cycle regulator expressed in the perinuclear area of human hematopoietic cells. The C-terminal region of MS4A3 interacts with cdc-associated phosphatase (KAP), enhancing its activity on cyclin-dependent kinase 2 (cdk2) and facilitating G(0)/G(1) arrest. The combined non-membrane segments of the 214 amino acid (aa), 25 kDa human MS4A3 show 53% and 52% aa identity with corresponding regions of mouse and rat MS4A3, respectively.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

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FAQs for MS4A3 Antibody (FAB6247U) (0)

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Secondary Antibodies

 

Isotype Controls

Other Available Formats

Alexa Fluor 350 FAB6247U
Alexa Fluor 405 FAB6247V
Alexa Fluor 488 FAB6247G
Alexa Fluor 594 FAB6247T
Alexa Fluor 647 FAB6247R
Alexa Fluor 700 FAB6247N
Alexa Fluor 750 FAB6247S
Fluorescein FAB6247F

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Bioinformatics

Gene Symbol MS4A3
Uniprot