MRPL40 Antibody

Western Blot: MRPL40 Antibody [H00064976-B01P] - Analysis of MRPL40 expression in transfected 293T cell line by MRPL40 polyclonal antibody. Lane 1: MRPL40 transfected lysate(22.77 KDa). Lane 2: Non-transfected lysate.

• Reactivity: Hu
• Applications: WB, ELISA
• Clonality: Polyclonal
• Host: Mouse
• Conjugate: Unconjugated

MRPL40 Antibody Summary

• Immunogen: MRPL40 (AAH09707, 1 a.a. ~ 207 a.a) fullAAH09707length human protein.MTASVLRSISLALRPTSGLLGTWQTQLRETHQRASLLSFWELIPMRSEPLRKKKKVDPKKDQEAKERLKRKIRKLEKATQELIPIEDFITPLKFLDKARERPQVELTFEETERRALLLKKWSLYKQQERKMERDTIRAMLEAQQEALEELQLESPKLHAEAIKRDPNLFPFEKEGPHYTPPIPNYQPPEGRYNDITKVYTQVEFKR
• Marker: Mitochondrial Matrix Marker
• Specificity: MRPL40 - mitochondrial ribosomal protein L40,
• Isotype: IgG
• Clonality: Polyclonal
• Host: Mouse
• Gene: MRPL40
• Purity: Protein A purified

Applications/Dilutions

• Dilutions:
  • Western Blot 1:500
  • ELISA
• Application Notes: Antibody reactive against Recombinant Protein with GST tag on ELISA and Western Blot and also on transfected lysate in western blot. GST tag alone is used as a negative control.
• Positive Control:

  MRPL40 Lysate (NBP2-64845)

Reactivity Notes

Human.

Packaging, Storage & Formulations

• Storage: Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
• Buffer: PBS (pH 7.4)
• Preservative: No Preservative
• Purity: Protein A purified

Notes

This product is produced by and distributed for Abnova, a company based in Taiwan.

Alternate Names for MRPL40 Antibody

• FLJ41774
• L40mt
• MGC9400
• mitochondrial ribosomal protein L40
• MRP-L22,39S ribosomal protein L40, mitochondrial
• MRP-L40
• NLVCFURIM
• nuclear localization signal containing protein deleted in velocardiofacialsyndrome
• nuclear localization signal deleted in velocardiofacial syndrome
• Nuclear localization signal-containing protein deleted in velocardiofacialsyndrome
• Up-regulated in metastasis

Background

Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein. Deletions in this gene may contribute to the etiology of velo-cardio-facial syndrome and DiGeorge syndrome. [provided by RefSeq]

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: MRPL40
• Entrez:
  • 64976(Human)
• Uniprot:
  • AAH09707(Human)