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Alternate Names for Mouse TL1A/TNFSF15 DuoSet ELISA, 5 Plate
TL1Vascular endothelial cell growth inhibitor
TNF superfamily ligand TL1A
tumor necrosis factor (ligand) superfamily, member 15
tumor necrosis factor ligand superfamily member 15
vascular endothelial growth inhibitor-192A
VEGITNF ligand-related molecule 1
TL1A is a type II transmembrane protein belonging to the TNF superfamily and has been designated TNF superfamily member 15 (TNFSF15). TL1A is predominantly expressed in endothelial cells and its expression is inducible by TNF-alpha and IL-1alpha. TL1A binds with high affinity to death receptor 3 (DR3), now known as TNFRSF25. Depending on the cell context, ligation of DR3 by TL1A can trigger one of two signaling pathways, activation of the transcription factor NF-kB, or activation of caspases and apoptosis.