Human DcR3/TNFRSF6B DuoSet ELISA, 15 Plate

• Reactivity: Hu
• Applications: ELISA
• Conjugate: Biotin

Human DcR3/TNFRSF6B DuoSet ELISA, 15 Plate Summary

• Source: N/A
• Assay Type: Solid Phase Sandwich ELISA
• Inter-Assay: See PDF Datasheet for details
• Intra-Assay: See PDF Datasheet for details
• Spike Recovery: See PDF Datasheet for details
• Sample Volume: See PDF Datasheet for details
• Gene: TNFRSF6B

Applications/Dilutions

• Dilutions:
  • ELISA
• Application Notes: No significant interference observed with available related molecules.

Packaging, Storage & Formulations

• Storage: Store the unopened product at 2 - 8 °C. Do not use past expiration date.

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for Human DcR3/TNFRSF6B DuoSet ELISA, 15 Plate

• DcR3
• DCR3Decoy receptor for Fas ligand
• Decoy receptor 3
• M68
• M68DJ583P15.1.1
• TNFRSF6B
• TR6
• TR6DcR3
• tumor necrosis factor receptor superfamily member 6B
• tumor necrosis factor receptor superfamily, member 6b, decoy

Background

Decoy receptor 3 (DcR3), also called TNFRSF6B, TR6 and M68, is a member of the TNF receptor superfamily. DcR3 lacks a transmembrane sequence and is a secreted protein. DcR3 shares sequence identity with OPG (31%), TNF RII (29%) and Fas (17%), and is expressed in a variety of different tissues and at high levels in many malignant tumors.

Publications for DcR3/TNFRSF6B (DY142)(14)

Publications using DY142

• NL Wu, DY Huang, SL Hsieh, YS Dai, WW Lin Decoy receptor 3 is involved in epidermal keratinocyte commitment to terminal differentiation via EGFR and PKC activation Experimental & Molecular Medicine, 2022-04-27;54(4):542-551. 2022-04-27 [PMID: 35478210] (Human)
• DY Liang, S Sha, Q Yi, J Shi, Y Chen, Y Hou, Q Chang Hepatitis B X protein upregulates decoy receptor 3 expression via the PI3K/NF-?B pathway Cell. Signal., 2019-06-21;62(0):109346. 2019-06-21 [PMID: 31229617] (Human)
• H Ge, C Liang, Z Li, D An, S Ren, C Yue, J Wu DcR3 induces proliferation, migration, invasion, and EMT in gastric cancer cells via the PI3K/AKT/GSK-3?/?-catenin signaling pathway Onco Targets Ther, 2018-07-19;11(0):4177-4187. 2018-07-19 [PMID: 30050309] (Human)
• C Liang, Y Xu, G Li, T Zhao, F Xia, G Li, D Zhang, J Wu Downregulation of DcR3 sensitizes hepatocellular carcinoma cells to TRAIL-induced apoptosis Onco Targets Ther, 2017-01-18;10(0):417-428. 2017-01-18 [PMID: 28176915] (Human)
• Chin-Chung Shu, Chia-Lin Hsu, Chih-Yuan Lee, Vin-Cent Wu, Feng-Jung Yang, Jann-Yuan Wang, Chong-Jen Yu, Li-Na Lee Inflammatory markers and clinical characteristics for predicting persistent positivity of interferon gamma release assay in dialysis population. Scientific Reports, 2016-10-05;0(0):2045-2322. 2016-10-05 [PMID: 27703202] (Human)
• Spiros D Ladas Elevated Serum Levels of the Antiapoptotic Protein Decoy-Receptor 3 Are Associated with Advanced Liver Disease Can J Gastroenterol Hepatol, 2016-08-09;2016(0):2637010. 2016-08-09 [PMID: 27595094] (Human)
• Jurado-Camino T, Cordoba R, Esteban-Burgos L, Hernandez-Jimenez E, Toledano V, Hernandez-Rivas J, Ruiz-Sainz E, Cobo T, Siliceo M, Perez de Diego R, Belda C, Cubillos-Zapata C, Lopez-Collazo E Chronic lymphocytic leukemia: a paradigm of innate immune cross-tolerance. J Immunol, 2014-12-10;194(2):719-27. 2014-12-10 [PMID: 25505275] (Human)
• Shu , Chin-Chu, Wu , Ming-Fan, Hsu , Chia-Lin, Huang , Chun-Ta, Wang , Jann-Yua, Hsieh , Shie-Lia, Yu , Chong-Je, Lee , Li-Na, Yang , Pan-Chyr Apoptosis-associated biomarkers in tuberculosis: promising for diagnosis and prognosis prediction. BMC Infect Dis, 2013-01-28;13(0):45. 2013-01-28 [PMID: 23356448] (Human)
• DcR3 binds to ovarian cancer via heparan sulfate proteoglycans and modulates tumor cells response to platinum with corresponding alteration in the expression of BRCA1. BMC Cancer, 2012-05-14;12(0):176. 2012-05-14 [PMID: 22583667] (Human)
• Wang W, Sun W, Zhang L Comment on "Decoy receptor 3 expression in AsPC-1 human pancreatic adenocarcinoma cells via the phosphatidylinositol 3-kinase-, Akt-, and NF-kappa B-dependent pathway". J. Immunol., 2009-08-15;183(4):2203; author. 2009-08-15 [PMID: 19661264] (Human)
• Chen CY, Yang KY, Chen MY, Chen HY, Lin MT, Lee YC, Perng RP, Hsieh SL, Yang PC, Chou TY Decoy receptor 3 levels in peripheral blood predict outcomes of acute respiratory distress syndrome. Am. J. Respir. Crit. Care Med., 2009-07-30;180(8):751-60. 2009-07-30 [PMID: 19644047] (Human)
• Mueller AM, Pedre X, Killian S, David M, Steinbrecher A The Decoy Receptor 3 (DcR3, TNFRSF6B) suppresses Th17 immune responses and is abundant in human cerebrospinal fluid. J. Neuroimmunol., 2009-03-06;209(1):57-64. 2009-03-06 [PMID: 19269042] (Human)
• Chen PH, Yang CR Decoy receptor 3 expression in AsPC-1 human pancreatic adenocarcinoma cells via the phosphatidylinositol 3-kinase-, Akt-, and NF-kappa B-dependent pathway. J. Immunol., 2008-12-15;181(12):8441-9. 2008-12-15 [PMID: 19050262] (Human)
• Chang YC, Chen TC, Lee CT, Yang CY, Wang HW, Wang CC, Hsieh SL Epigenetic control of MHC class II expression in tumor-associated macrophages by decoy receptor 3. Blood, 2008-03-18;111(10):5054-63. 2008-03-18 [PMID: 18349319] (Human)

Bioinformatics

• Gene Symbol: TNFRSF6B