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HAF008). A specific band was detected for TL1A/TNFSF15 at approximately 22 kDa (as indicated). This experiment was conducted under reducing conditions and using Immunoblot Buffer Group 1." class="big_lightbox" target="_blank">
MAB1050) followed by Goat anti-Rabbit IgG PE-conjugated Secondary Antibody (F0110) and Mouse anti-Human CCR9 APC-conjugated Monoclonal Antibody (FAB1791A). Cells were gated on CD4+ lymphocytes using Mouse anti-Human CD4 FITC-conjugated Monoclonal Antibody (FAB3791F). View our protocol for Staining Membrane-associated Proteins." class="big_lightbox" target="_blank">
VC003). Before incubation with the primary antibody, tissue was subjected to heat-induced epitope retrieval using Antigen Retrieval Reagent-Basic (CTS013). Tissue was stained using DAB (brown) and counterstained with hematoxylin (blue). Specific staining was localized to cytoplasm in epithelial cells. View our protocol for IHC Staining with VisUCyte HRP Polymer Detection Reagents." class="big_lightbox" target="_blank">
1319-TL) induces apoptosis in the TF-1 human erythroleukemic cell line in a dose-dependent manner (orange line), as measured by Resazurin (AR002). Apoptosis elicited by Recombinant Human TL1A/TNFSF15 (80 ng/mL) is neutralized (green line) by increasing concentrations of Rabbit Anti-Human TL1A/TNFSF15 Monoclonal Antibody (Catalog # MAB74422). The ND50 is typically 0.04‑0.2 µg/mL." class="big_lightbox" target="_blank">
AB-105-C, open histogram), followed by Allophycocyanin-conjugated Anti-Rabbit IgG Secondary Antibody (Catalog # F0111). View our protocol for Staining Membrane-associated Proteins. " class="big_lightbox" target="_blank">
VEGI is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This protein is abundantly expressed in endothelial cells, but is not expressed in either B or T cells. The expression of this protein is inducible by TNF and IL-1 alpha. This cytokine is a ligand for receptor TNFRSF25 and decoy receptor TNFRSF21/DR6. It can activate NF-kappaB and MAP kinases, and acts as an autocrine factor to induce apoptosis in endothelial cells. This cytokine is also found to inhibit endothelial cell proliferation, and thus may function as an angiogenesis inhibitor. An additional isoform encoded by an alternatively spliced transcript variant has been reported but the sequence of this transcript has not been determined
![Western Blot TL1A/TNFSF15 Antibody (2116A) [Unconjugated]](http://images.novusbio.com/images/antibody/TL1A_MAB74422_Western_Blot_23091.jpg)
![N/A TL1A/TNFSF15 [Biotin]](http://images.novusbio.com/fullsize/elisa/DATA_TL1A_DY131905_ELISA_2352.jpg)
![N/A TL1A/TNFSF15 [Biotin]](http://images.novusbio.com/fullsize/elisa/DATA_TL1A_DY189605_ELISA_2376.jpg)
![Flow Cytometry TL1A/TNFSF15 Antibody (2116A) [Unconjugated]](http://images.novusbio.com/images/antibody/TL1A_MAB74422_Flow_Cytometry_22982.jpg)
![Immunohistochemistry TL1A/TNFSF15 Antibody (2116A) [Unconjugated]](http://images.novusbio.com/images/antibody/TL1A_MAB74422_Immunohistochemistry_23132.jpg)
![Neutralization TL1A/TNFSF15 Antibody (2116A) [Unconjugated]](http://images.novusbio.com/images/antibody/TL1A_MAB74422_Block_Neutralize_23289.jpg)
![Flow Cytometry TL1A/TNFSF15 Antibody (2116A) [Unconjugated]](http://images.novusbio.com/images/mab74422_human-tl1a-tnfsf15-mab-clone-2116a-flow-cytometry-2672023163155..jpg)
