Mouse ST2/IL-33R DuoSet ELISA, 15 Plate

• Reactivity: Mu
• Applications: ELISA
• Conjugate: Biotin

Mouse ST2/IL-33R DuoSet ELISA, 15 Plate Summary

• Source: N/A
• Assay Type: Solid Phase Sandwich ELISA
• Inter-Assay: See PDF Datasheet for details
• Intra-Assay: See PDF Datasheet for details
• Spike Recovery: See PDF Datasheet for details
• Sample Volume: See PDF Datasheet for details
• Gene: Il1rl1

Applications/Dilutions

• Dilutions:
  • ELISA
• Application Notes: No significant interference observed with available related molecules.

Packaging, Storage & Formulations

• Storage: Store the unopened product at 2 - 8 °C. Do not use past expiration date.

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for Mouse ST2/IL-33R DuoSet ELISA, 15 Plate

• DER4
• DER4ST2growth stimulation-expressed
• Fit-1
• IL-1 R4
• IL1R4
• IL-1R4
• IL-1RL1
• IL-33 R
• IL33R
• IL-33R
• interleukin 1 receptor-like 1
• interleukin 1 receptor-related protein
• interleukin-1 receptor-like 1
• Ly84
• MGC32623
• Protein ST2
• ST2
• ST2L
• ST2V
• T1
• T1homolog of mouse growth stimulation-expressed

Background

ST2, also known as IL-1 R4, is a component of the receptor for the proinflammatory cytokine Interleukin-33. The IL-33 receptor additionally includes IL-1 RAcp which also associates with IL-1 RI and IL-1 R rp2/IL-1 R6. A soluble form of ST2 functions as a decoy receptor. IL-33 promotes Th2-biased immune responses, resulting in eosinophilia, mast cell activation, and allergic inflammation. In addition, IL-33 enhances inflammation-associated hypernociception and protects from atherosclerosis and cardiac myocyte hypertrophy. Soluble ST2 is elevated in the serum under inflammatory conditions including allergic asthma, sepsis, trauma, dengue fever, pulmonary disease, and lupus. It is also associated aortic stenosis, congestive cardiomyopathy, and risk of cardiovascular heart failure and death.

Publications for ST2/IL-33R (DY1004)(2)

Publications using DY1004

• Paulissen G, El Hour M, Rocks N, Gueders M, Bureau F, Foidart J, Lopez-Otin C, Noel A, Cataldo D Control of allergen-induced inflammation and hyperresponsiveness by the metalloproteinase ADAMTS-12. J Immunol, 2012-09-07;189(8):4135-43. 2012-09-07 [PMID: 22962682] (Mouse)
• Hsu CL, Neilsen CV, Bryce PJ IL-33 is produced by mast cells and regulates IgE-dependent inflammation. PLoS ONE, 2010-08-03;5(8):e11944. 2010-08-03 [PMID: 20689814] (Mouse)

Bioinformatics

• Gene Symbol: Il1rl1