Mouse Pentraxin 3/TSG-14 Quantikine ELISA Kit

Product Discontinued

Mouse Pentraxin 3/TSG-14 Quantikine ELISA Kit Summary

• Background: The Quantikine Mouse Pentraxin 3 Immunoassay is a 4.5 hour solid-phase ELISA designed to measure mouse PTX3 in cell culture supernates, serum, and plasma. It contains NS0-expressed recombinant mouse PTX3 and antibodies raised against the recombinant factor. This immunoassay has been shown to accurately quantitate the recombinant factor. Results obtained using natural mouse PTX3 showed linear... curves that were parallel to the standard curves obtained using the Quantikine kit standards. These results indicate that this kit can be used to determine relative mass values for naturally occurring mouse PTX3.
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• Specificity: Natural and recombinant mouse PTX3
• Source: N/A
• Assay Type: Solid Phase Sandwich ELISA
• Inter-Assay: See PDF Datasheet for details
• Intra-Assay: See PDF Datasheet for details
• Spike Recovery: See PDF Datasheet for details
• Sample Volume: See PDF Datasheet for details
• Gene: Ptx3

Applications/Dilutions

• Dilutions:
  • ELISA
• Application Notes: No significant interference observed with available related molecules.

Packaging, Storage & Formulations

• Storage: Store the unopened product at 2 - 8 °C. Do not use past expiration date.

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for Mouse Pentraxin 3/TSG-14 Quantikine ELISA Kit

• alpha-induced protein 5
• pentaxin-related gene, rapidly induced by IL-1 beta, tumor necrosis factor
• Pentaxin-related protein PTX3
• Pentraxin 3
• pentraxin 3, long
• pentraxin-3
• pentraxin-related gene, rapidly induced by IL-1 beta
• pentraxin-related protein PTX3
• PTX3
• TNF alpha-induced protein 5
• TNFAIP5
• TSG14
• TSG-14
• TSG-14pentaxin-related gene, rapidly induced by IL-1 beta
• Tumor necrosis factor alpha-induced protein 5
• tumor necrosis factor, alpha-induced protein 5
• Tumor necrosis factor-inducible gene 14 protein
• tumor necrosis factor-inducible protein TSG-14

Background

Pentraxin 3 (PTX3), also known as TNF-stimulated gene 14 (TSG-14), is a secreted glycoprotein belonging to the Pentraxin family of proteins. It is the prototypical long Pentraxin, exhibiting a C-terminal Pentraxin domain characteristic of the family, and a unique N-terminal domain. It is produced by several cell types including endothelial and mononuclear cells. PTX3 acts as a pattern recognition receptor with non-redundant roles in the innate immune response to several microbial agents including the fungal pathogen Aspergillus fumigatus. Overexpression leads to enhanced pro-inflammatory responses. PTX3 is induced in response to LPS and inflammatory cytokines including TNF-alpha and IL-1 beta.

⚠ WARNING: This product can expose you to chemicals including N,N-Dimethylforamide, which is known to the State of California to cause cancer. For more information, go to www.P65Warnings.ca.gov.

Publications for Pentraxin 3/TSG-14 (MPTX30)(6)

Publications using MPTX30

• Wang, W;Wang, Y;Yuan, C;Cao, F;Tang, W;Zhu, Q;Dong, X;Deng, L;Lu, G;Xia, Q;Chen, W; Pentraxin3 exacerbates acute pancreatitis injury by inhibiting oxidative phosphorylation pathway Scientific reports 2025-02-26 [PMID: 40011615] (Mouse)
• D Coltrini, AMK Chandran, M Belleri, PL Poliani, M Cominelli, F Pagani, M Capra, S Calza, S Prioni, L Mauri, A Prinetti, JK Kofler, ML Escolar, M Presta beta-Galactosylceramidase Deficiency Causes Upregulation of Long Pentraxin-3 in the Central Nervous System of Krabbe Patients and Twitcher Mice International Journal of Molecular Sciences, 2022-08-21;23(16):. 2022-08-21 [PMID: 36012705] (Mouse)
• Y Takahashi, R Watanabe, Y Sato, N Ozawa, M Kojima, K Watanabe-K, R Shirai, K Sato, T Hirano, T Watanabe Novel phytopeptide osmotin mimics preventive effects of adiponectin on vascular inflammation and atherosclerosis Metab. Clin. Exp., 2018-02-02;0(0):. 2018-02-02 [PMID: 29410350] (Mouse)
• Yao G, Liang M, Liang N, Yin M, Lu M, Lian J, Wang Y, Sun F MicroRNA-224 is involved in the regulation of mouse cumulus expansion by targeting Ptx3. Mol Cell Endocrinol, 2013-10-18;382(1):244-53. 2013-10-18 [PMID: 24145127] (Mouse)
• Chen , Jianlin, Matzuk , Martin M, Zhou , Xin J, Lu , Christop Endothelial pentraxin 3 contributes to murine ischemic acute kidney injury. Kidney Int, 2012-08-15;82(11):1195-207. 2012-08-15 [PMID: 22895517] (Mouse)
• Han , Bing, Ma , Xuezhong, Zhang , Jianhua, Zhang , Yu, Bai , Xiaohui, Hwang , David M, Keshavjee , Shaf, Levy , Gary A, McGilvray , Ian, Liu , Mingyao Protective effects of long pentraxin PTX3 on lung injury in a severe acute respiratory syndrome model in mice. Lab Invest, 2012-06-25;92(9):1285-96. 2012-06-25 [PMID: 22732935] (Mouse)

FAQs for Pentraxin 3/TSG-14 (MPTX30). (Showing 1 - 1 of 1 FAQs).

1. wondering what the difference is between your quantikine and duo set elisas?
   • Usually the duosets do not have the entire kit such as plates and buffers, whereas the other kits are complete.

Bioinformatics

• Gene Symbol: Ptx3