Mouse IL-33 DuoSet ELISA, 15 Plate

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Product Details

Summary
Reactivity MuSpecies Glossary
Applications ELISA
Conjugate
Biotin

Order Details

Mouse IL-33 DuoSet ELISA, 15 Plate Summary

Source
N/A
Assay Type
Solid Phase Sandwich ELISA
Inter-Assay
See PDF Datasheet for details
Intra-Assay
See PDF Datasheet for details
Spike Recovery
See PDF Datasheet for details
Sample Volume
See PDF Datasheet for details
Gene
Il33

Applications/Dilutions

Dilutions
  • ELISA
Application Notes
No significant interference observed with available related molecules.
Publications
Read Publications using DY3626.

Packaging, Storage & Formulations

Storage
Store the unopened product at 2 - 8 °C. Do not use past expiration date.

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for Mouse IL-33 DuoSet ELISA, 15 Plate

  • C9orf26
  • C9orf26chromosome 9 open reading frame 26 (NF-HEV)
  • DKFZp586H0523
  • DVS27
  • DVS27-related protein
  • IL1F11
  • IL-1F11
  • IL33
  • IL-33
  • interleukin 33
  • Interleukin-1 family member 11
  • interleukin-33
  • NFHEV
  • NF-HEV
  • NF-HEVNFEHEV
  • Nuclear factor from high endothelial venules
  • RP11-575C20.2

Background

IL-33 (Interleukin-33) is released from physically damaged or necrotic cells. It triggers Th2-biased immune cell activation at sites of inflammation as well as regulatory T cell and M2 macrophage expansion. It additionally induces angiogenesis, promotes tumor cell migration and invasion, limits cardiac myocyte hypertrophy, and limits the development of atherosclerotic plaques. IL-33 signals through a receptor complex composed of ST2 and IL-1 RAcP. IL-1 RAcP also associates with IL-1 RI, IL-1 RII, IL-1 R6, and SCF R/c-kit. Soluble isoforms of ST2 and IL-1 RAcP function as decoy receptors that regulate IL-33 bioactivity.

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Publications for IL-33 (DY3626)(58)

We have publications tested in 3 confirmed species: Mouse, Rat, Transgenic Mouse.


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Mouse
(57)
Rat
(2)
Transgenic Mouse
(3)
All Species
Showing Publications 1 - 10 of 58. Show All 58 Publications.
Publications using DY3626 Applications Species
Cook, PC;Brown, SL;Houlder, EL;Furlong-Silva, J;Conn, DP;Colombo, SAP;Baker, S;Svedberg, FR;Howell, G;Bertuzzi, M;Boon, L;Konkel, JE;Thornton, CR;Allen, JE;MacDonald, AS; Mgl2+ cDC2s coordinate fungal allergic airway type 2, but not type 17, inflammation in mice Nature communications 2025-01-22 [PMID: 39843887] (Mouse) Mouse
Schumacher, MA;Thai, MH;Hsieh, JJ;Gramajo, A;Liu, CY;Frey, MR; Wnt/?-catenin maintains epithelial IL-33 in the colonic stem and progenitor cell niche and drives its induction in colitis Mucosal immunology 2024-11-24 [PMID: 39592069] (Mouse) Mouse
Agner, K;McQuade, VL;Womble, J;Guttenberg, MA;Phatak, S;Ingram, JL; Withaferin A reduces pulmonary eosinophilia and IL-25 production in a mouse model of allergic airways disease bioRxiv : the preprint server for biology 2024-08-26 [PMID: 39253456] (Mouse) Mouse
Hussain, S;Majumder, N;Mazumder, MHH;Lewis, SE;Olapeju, O;Velayutham, M;Amin, MS;Brundage, K;Kelley, EE;Vanoirbeek, J; Intermittent ozone inhalation during house dust mite-induced sensitization primes for adverse asthma phenotype Redox biology 2024-10-01 [PMID: 39244793] (Mouse) Mouse
Mattar, P;Reginato, A;Lavados, C;Das, D;Kalyani, M;Martinez-Lopez, N;Sharma, M;Skovbjerg, G;Skytte, JL;Roostalu, U;Subbarayan, R;Picarda, E;Zang, X;Zhang, J;Guha, C;Schwartz, G;Rajbhandari, P;Singh, R; Insulin and leptin oscillations license food-entrained browning and metabolic flexibility Cell reports 2024-06-19 [PMID: 38900636] (Mouse, Transgenic Mouse) Mouse, Transgenic Mouse
Jiao, M;Wang, C;Tang, X;Dai, C;Zhang, N;Fan, A;Qian, Z;Liu, S;Zhang, F;Li, B;Xu, Y;Tan, Z;Gong, F;Lu, Y;Zheng, F; Active secretion of IL-33 from astrocytes is dependent on TMED10 and promotes central nervous system homeostasis Brain, behavior, and immunity 2024-04-24 [PMID: 38663774] (Mouse, Transgenic Mouse) Mouse, Transgenic Mouse
Ajendra, J;Papotto, PH;Parkinson, JE;Dodd, RJ;Bombeiro, AL;Pearson, S;Chan, BHK;Ribot, JC;McSorley, HJ;Sutherland, TE;Allen, JE; The IL-17A-neutrophil axis promotes epithelial cell IL-33 production during nematode lung migration Mucosal immunology 2023-09-30 [PMID: 37783278] (Mouse, Transgenic Mouse) Mouse, Transgenic Mouse
Hollifield, IE;Motyka, NI;Fernando, KA;Bitoun, JP; Heat-Labile Enterotoxin Decreases Macrophage Phagocytosis of Enterotoxigenic Escherichia coli Microorganisms 2023-08-21 [PMID: 37630681] (Mouse) Mouse
Takimoto-Sato, M;Suzuki, M;Kimura, H;Ge, H;Matsumoto, M;Makita, H;Arai, S;Miyazaki, T;Nishimura, M;Konno, S; Apoptosis inhibitor of macrophage (AIM)/CD5L is involved in the pathogenesis of COPD Respiratory research 2023-08-17 [PMID: 37592330] (Mouse) Mouse
Maggi, L;Camelo, GMA;Rocha, IC;Pereira Alves, W;Moreira, JMP;Almeida Pereira, T;Tafuri, WL;Rabelo, ÉML;Correa, A;Ecco, R;Negrão-Corrêa, DA; Role of the IL-33/ST2 Activation Pathway in the Development of the Hepatic Fibrosis Induced by Schistosoma mansoni Granulomas in Mice International journal of molecular sciences 2023-06-16 [PMID: 37373379] (Mouse) Mouse
Show All 58 Publications.

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Product General Protocols

Find general support by application which include: protocols, troubleshooting, illustrated assays, videos and webinars.

FAQs for IL-33 (DY3626). (Showing 1 - 1 of 1 FAQs).

  1. What is the difference between the Quantikine and Duoset ELISA kits?
    • Our Quantikine kits are fully optimized and validated for the sample types listed on the product specific webpage and datasheet, as this can vary between kits. Each kit is supplied ready to use with one pre-coated 96-well plate, a detection antibody directly conjugated to HRP, and all other necessary reagents. These kits are ideal for researchers who want the convenience of a ready to use and optimized ELISA product. Some of these kits are also available prepackaged in larger 6 and 50 plate sizes.Our DuoSet Kits, in contrast, are ELISA development kits containing the capture and detection antibody, the mass-value calibrated standard, and streptavidin-HRP to prepare approximately 5 or 15 plates. Ancillary reagents will need to be used/purchased, and for most kits, we will recommend one of our Ancillary Reagent Kits, which contain the reagents we use ourselves in-house. DuoSet kits are validated only for cell culture supernatant samples and therefore require further development and validation for accurate measurement in more complex samples such as serum and plasma. Our DuoSet Kits offer an economical, flexible alternative for the experienced ELISA user.

Additional IL-33 Products

Blogs on IL-33.

Interleukin 33 (IL-33) - A dual function cytokine
IL-33 is a member of the interleukin family of cytokines that regulates a wide variety of cellular functions. Its receptor is ST2, an IL-1 receptor family member that also acts as a negative regulator of TLR-IL-1R signaling and the IL-1R accessory ...  Read full blog post.

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Bioinformatics

Gene Symbol Il33