Mouse IL-22 DuoSet ELISA, 15 Plate

• Reactivity: Mu
• Applications: ELISA
• Conjugate: Biotin

Mouse IL-22 DuoSet ELISA, 15 Plate Summary

• Source: N/A
• Assay Type: Solid Phase Sandwich ELISA
• Inter-Assay: See PDF Datasheet for details
• Intra-Assay: See PDF Datasheet for details
• Spike Recovery: See PDF Datasheet for details
• Sample Volume: See PDF Datasheet for details
• Gene: Il22

Applications/Dilutions

• Dilutions:
  • ELISA
• Application Notes: No significant interference observed with available related molecules.

Packaging, Storage & Formulations

• Storage: Store the unopened product at 2 - 8 °C. Do not use past expiration date.

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for Mouse IL-22 DuoSet ELISA, 15 Plate

• Cytokine Zcyto18
• IL-10-related T-cell-derived inducible factor
• IL22
• IL-22
• IL-D110
• IL-TIF
• ILTIFIL-10-related T-cell-derived-inducible factor
• IL-TIFMGC79382
• interleukin 22
• interleukin-22
• MGC79384
• TIFa
• TIFIL-23
• zcyto18

Background

IL-22 (Interleukin-22) is a cytokine that induces the production of reactive oxygen species, IL-6, IL-10, and TNF-alpha as well as neutrophil infiltration during inflammation. It also supports the integrity of epithelial barriers and induces epithelial cell proliferation during wound healing. IL-22 signals through a receptor complex consisting of IL-22 R and IL-10 R beta. IL-10 R beta is a shared component of the receptor complexes for IL-10, IL-26, IL-28, and IL-29. IL-22 additionally binds to IL-22BP which blocks the interaction of IL-22 with IL-22 R.

Publications for IL-22 (DY582)(33)

Publications using DY582

• Griffith, BD;Kadiyala, P;McGue, J;Sun, L;Kumar, A;Espinoza, CE;Donahue, KL;Iyer, MK;Speyer, C;Nelson, S;Spiteri, A;Elhossiny, AM;Brown, K;Attebury, H;Bednar, F;Carpenter, ES;Kryczek, I;Zhang, Y;Zou, W;Pasca di Magliano, M;Frankel, TL; Aryl hydrocarbon receptor ligands drive pancreatic cancer initiation and progression through pro-tumorigenic T cell polarization Cancer discovery 2025-09-04 [PMID: 40905825] (Mouse, Transgenic Mouse)
• Xu, B;Mattapallil, MJ;Jia, X;Tang, J;Horai, R;Caspi, RR;Gery, I; Laquinimod treatment attenuates EAU by inhibiting both the inductive and effector phases in an APC-dependent manner bioRxiv : the preprint server for biology 2025-05-25 [PMID: 40492200] (Mouse)
• Antos, D;Parks, OB;Duray, AM;Abraham, N;Michel, JJ;Kupul, S;Westcott, R;Alcorn, JF; Cell-intrinsic regulation of phagocyte function by interferon lambda during pulmonary viral, bacterial super-infection PLoS pathogens 2024-08-23 [PMID: 39178311] (Mouse)
• Kelly, AM;McCarthy, KN;Claxton, TJ;Carlile, SR;O'Brien, EC;Vozza, EG;Mills, KH;McLoughlin, RM; IL-10 inhibition during immunization improves vaccine-induced protection against Staphylococcus aureus infection JCI insight 2024-05-28 [PMID: 38973612] (Mouse)
• Canali, S;Fischer, AW;Nguyen, M;Anderson, K;Wu, L;Graham, AR;Hsiao, CJ;Bankar, C;Dussault, N;Ritchie, V;Goodridge, M;Sparrow, T;Pannoni, A;Tse, SW;Woo, V;Klovdahl, K;Iacovelli, J;Huang, E; Lipid-encapsulated mRNA encoding an extended serum half-life interleukin-22 ameliorates metabolic disease in mice Molecular metabolism 2024-06-11 [PMID: 38871178] (Mouse)
• Lim, JS;Jeon, EJ;Go, HS;Kim, HJ;Kim, KY;Nguyen, TQT;Lee, DY;Kim, KS;Pietrocola, F;Hong, SH;Lee, SE;Kim, KS;Park, TS;Choi, DH;Jeong, YJ;Park, JH;Kim, HS;Min, JJ;Kim, YS;Park, JT;Cho, JH;Lee, GW;Lee, JH;Choy, HE;Park, SC;Lee, CH;Rhee, JH;Serrano, M;Cho, KA; Mucosal TLR5 activation controls healthspan and longevity Nature communications 2024-01-02 [PMID: 38167804] (Mouse)
• Maggi, L;Camelo, GMA;Rocha, IC;Pereira Alves, W;Moreira, JMP;Almeida Pereira, T;Tafuri, WL;Rabelo, ÉML;Correa, A;Ecco, R;Negrão-Corrêa, DA; Role of the IL-33/ST2 Activation Pathway in the Development of the Hepatic Fibrosis Induced by Schistosoma mansoni Granulomas in Mice International journal of molecular sciences 2023-06-16 [PMID: 37373379] (Mouse)
• KK Jang, T Heaney, M London, Y Ding, F Yeung, D Ercelen, YH Chen, J Axelrad, S Gurunathan, A Marijke Ke, ME Griffin, HC Hang, K Cadwell Antimicrobial overproduction sustains intestinal inflammation by inhibiting Enterococcus colonization bioRxiv : the preprint server for biology, 2023-02-01;0(0):. 2023-02-01 [PMID: 36778381] (Mouse)
• H Jeong, EH Hong, JH Ahn, J Cho, JH Jeong, CW Kim, BI Yoon, JH Koo, YY Park, YM Yang, T Iwawaki, BA Vallance, SY Chang, HJ Ko ERdj5 protects goblet cells from endoplasmic reticulum stress-mediated apoptosis under inflammatory conditions Experimental & Molecular Medicine, 2023-02-09;0(0):. 2023-02-09 [PMID: 36759578] (Mouse)
• A Ulu, S Sveiven, A Bilg, JV Velazquez, M Diaz, M Mukherjee, AG Yuil-Valde, S Kota, A Burr, A Najera, TM Nordgren IL-22 regulates inflammatory responses to agricultural dust-induced airway inflammation Toxicology and Applied Pharmacology, 2022-05-05;0(0):116044. 2022-05-05 [PMID: 35525330] (Mouse)
• M Arabpour, C Lebrero-Fe, K Schön, A Strömberg, V Börjesson, K Lahl, M Ballegeer, X Saelens, D Angeletti, W Agace, N Lycke ADP-ribosylating adjuvant reveals plasticity in cDC1 cells that drive mucosal Th17 cell development and protection against influenza virus infection Mucosal Immunology, 2022-04-13;0(0):. 2022-04-13 [PMID: 35418673] (Mouse)
• J Serré, AT Tanjeko, C Mathyssen, T Heigl, A Sacreas, DP Cook, E Verbeken, K Maes, J Verhaegen, C Pilette, J Vanoirbeek, C Gysemans, C Mathieu, B Vanaudenae, W Janssens, G Gayan-Rami Effects of repeated infections with non-typeable Haemophilus influenzae on lung in vitamin D deficient and smoking mice Respiratory Research, 2022-03-02;23(1):40. 2022-03-02 [PMID: 35236342] (Mouse)
• AM Porras, Q Shi, H Zhou, R Callahan, G Montenegro, N Solomons, IL Brito Geographic differences in gut microbiota composition impact susceptibility to enteric infection Cell Reports, 2021-07-27;36(4):109457. 2021-07-27 [PMID: 34320343] (Mouse)
• R Nehmar, L Fauconnier, J Alves-Filh, D Togbe, A DeCauwer, S Bahram, M Le Bert, B Ryffel, P Georgel Aryl hydrocarbon receptor (Ahr)-dependent Il-22 expression by type 3 innate lymphoid cells control of acute joint inflammation Journal of Cellular and Molecular Medicine, 2021-03-18;0(0):. 2021-03-18 [PMID: 33734594] (Mouse)
• T Castro-Dop, A Fleming, TW Dennison, JR Ferdinand, K Harcourt, BJ Stewart, Z Cader, ZK Tuong, C Jing, LSC Lok, RJ Mathews, A Portet, A Kaser, S Clare, MR Clatworthy GM-CSF Calibrates Macrophage Defense and Wound Healing Programs during Intestinal Infection and Inflammation Cell Rep, 2020-07-07;32(1):107857. 2020-07-07 [PMID: 32640223] (Mouse)
• J Hrdý, J Alard, A Couturier-, O Boulard, D Boutillier, M Delacre, C Lapadatesc, A Cesaro, P Blanc, B Pot, B Ryffel, M Chamaillar, C Grangette Lactobacillus reuteri 5454 and Bifidobacterium animalis ssp. lactis 5764 improve colitis while differentially impacting dendritic cells maturation and antimicrobial responses Sci Rep, 2020-03-24;10(1):5345. 2020-03-24 [PMID: 32210304] (Mouse)
• P Saha, BS Yeoh, X Xiao, RM Golonka, V Singh, Y Wang, M Vijay-Kuma PAD4-dependent NETs generation are indispensable for intestinal clearance of Citrobacter rodentium Mucosal Immunol, 2019-02-01;0(0):. 2019-02-01 [PMID: 30710097] (Mouse)
• CN Berger, VF Crepin, TI Roumelioti, JC Wright, N Serafini, M Pevsner-Fi, L Yu, E Elinav, JP Di Santo, JS Choudhary, G Frankel The Citrobacter rodentium type III secretion system effector EspO affects mucosal damage repair and antimicrobial responses PLoS Pathog., 2018-10-26;14(10):e1007406. 2018-10-26 [PMID: 30365535] (Mouse)
• P Zarin, TSH In, ELY Chen, J Singh, GW Wong, M Mohtashami, DL Wiest, MK Anderson, JC Zúñiga-Pfl Integration of T Cell Receptor, Notch and Cytokine Signals Programs in Mouse ?? T Cell Effector Differentiation Immunol. Cell Biol., 2018-06-28;0(0):. 2018-06-28 [PMID: 29754419] (Mouse)
• JS Bowers, MH Nelson, K Majchrzak, SR Bailey, B Rohrer, AD Kaiser, C Atkinson, L Gattinoni, CM Paulos Th17 cells are refractory to senescence and retain robust antitumor activity after long-term ex vivo expansion JCI Insight, 2017-03-09;2(5):e90772. 2017-03-09 [PMID: 28289713] (Mouse)
• Masahiro Yokosawa T-bet overexpression regulates AHR-mediated Th-17 differentiation through an IFN?-independent pathway Clin. Exp. Immunol, 2017-01-31;0(0):. 2017-01-31 [PMID: 27936495] (Mouse)
• Interleukin 7 immunotherapy improves host immunity and survival in a two-hit model of Pseudomonas aeruginosa pneumonia J Leukoc Biol, 2016-09-14;0(0):. 2016-09-14 [PMID: 27630218] (Mouse)
• Brown A, Murphy A, Lalor S, Leech J, O'Keeffe K, Mac Aogain M, O'Halloran D, Lacey K, Tavakol M, Hearnden C, Fitzgerald-Hughes D, Humphreys H, Fennell J, van Wamel W, Foster T, Geoghegan J, Lavelle E, Rogers T, McLoughlin R Memory Th1 Cells Are Protective in Invasive Staphylococcus aureus Infection. PLoS Pathog, 2015-11-05;11(11):e1005226. 2015-11-05 [PMID: 26539822] (Mouse)
• Mattsson J, Schon K, Ekman L, Fahlen-Yrlid L, Yrlid U, Lycke N Cholera toxin adjuvant promotes a balanced Th1/Th2/Th17 response independently of IL-12 and IL-17 by acting on Gsalpha in CD11b(+) DCs. Mucosal Immunol, 2014-11-26;8(4):815-27. 2014-11-26 [PMID: 25425266] (Mouse)
• Hayes M, Ovcinnikovs V, Smith A, Kimber I, Dearman R The aryl hydrocarbon receptor: differential contribution to T helper 17 and T cytotoxic 17 cell development. PLoS ONE, 2014-09-09;9(9):e106955. 2014-09-09 [PMID: 25203682] (Mouse)
• Macho-Fernandez E, Koroleva E, Spencer C, Tighe M, Torrado E, Cooper A, Fu Y, Tumanov A Lymphotoxin beta receptor signaling limits mucosal damage through driving IL-23 production by epithelial cells. Mucosal Immunol, 2014-09-03;8(2):403-13. 2014-09-03 [PMID: 25183367] (Mouse)
• Tatano Y, Shimizu T, Tomioka H Unique macrophages different from M1/M2 macrophages inhibit T cell mitogenesis while upregulating Th17 polarization. Sci Rep, 2014-02-20;4(0):4146. 2014-02-20 [PMID: 24553452] (Mouse)
• van Voorhis , Michael, Knopp , Samantha, Julliard , Walker, Fechner , John H, Zhang , Xiaoji, Schauer , James J, Mezrich , Joshua D Exposure to atmospheric particulate matter enhances Th17 polarization through the aryl hydrocarbon receptor. PLoS ONE, 2013-12-11;8(12):e82545. 2013-12-11 [PMID: 24349309] (Mouse)
• Kohler T, Reizis B, Johnson RS, Weighardt H, Forster I Influence of hypoxia-inducible factor 1-alpha on dendritic cell differentiation and migration. Eur. J. Immunol., 2012-05-01;42(5):1226-36. 2012-05-01 [PMID: 22539295] (Mouse)
• Dubin PJ, Martz A, Eisenstatt JR, Fox MD, Logar A, Kolls JK Interleukin-23-mediated inflammation in Pseudomonas aeruginosa pulmonary infection. Infect. Immun., 2011-10-24;80(1):398-409. 2011-10-24 [PMID: 22025517] (Mouse)
• Nakagome K, Imamura M, Kawahata K High expression of IL-22 suppresses antigen-induced immune responses and eosinophilic airway inflammation via an IL-10-associated mechanism. J. Immunol., 2011-10-12;187(10):5077-89. 2011-10-12 [PMID: 21998459] (Mouse)
• El-Behi M, Ciric B, Dai H The encephalitogenicity of T(H)17 cells is dependent on IL-1- and IL-23-induced production of the cytokine GM-CSF. Nat. Immunol., 2011-04-24;12(6):568-75. 2011-04-24 [PMID: 21516111] (Mouse)
• Blumberg H, Dinh H, Dean C, Trueblood ES, Bailey K, Shows D, Bhagavathula N, Aslam MN, Varani J, Towne JE, Sims JE IL-1RL2 and its ligands contribute to the cytokine network in psoriasis. J. Immunol., 2010-09-10;185(7):4354-62. 2010-09-10 [PMID: 20833839] (Mouse)

FAQs for IL-22 (DY582). (Showing 1 - 1 of 1 FAQs).

1. wondering what the difference is between your quantikine and duo set elisas?
   • Usually the duosets do not have the entire kit such as plates and buffers, whereas the other kits are complete.

Bioinformatics

• Gene Symbol: Il22