Mouse GM-CSF Quantikine ELISA Kit, 2 Plate

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Product Details

Summary
Reactivity MuSpecies Glossary
Applications ELISA
Conjugate
HRP

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Mouse GM-CSF Quantikine ELISA Kit, 2 Plate Summary

Background
The Quantikine Mouse GM-CSF Immunoassay is a 4.5 hour solid phase ELISA designed to measure mouse GM-CSF in cell culture supernates and serum. It contains E. coli-expressed recombinant mouse GM-CSF and antibodies raised against the recombinant factor. This immunoassay has been shown to quantitate the recombinant mouse GM-CSF accurately. Results obtained using natural mouse GM-CSF sh...owed dose-response curves that were parallel to the standard curves obtained using the recombinant standards. These results indicate that this kit can be used to determine relative mass values for natural mouse GM-CSF.
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Specificity
Natural and recombinant mouse GM-CSF
Assay Type
Solid Phase Sandwich ELISA
Inter-Assay
See PDF Datasheet for details
Intra-Assay
See PDF Datasheet for details
Spike Recovery
See PDF Datasheet for details
Sample Volume
See PDF Datasheet for details
Gene
Csf2

Applications/Dilutions

Application Notes
No significant interference observed with available related molecules.
Publications
Read Publications using MGM00.

Packaging, Storage & Formulations

Storage
Store the unopened product at 2 - 8 °C. Do not use past expiration date.

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for Mouse GM-CSF Quantikine ELISA Kit, 2 Plate

  • colony stimulating factor 2 (granulocyte-macrophage)
  • Colony-stimulating factor
  • CSF
  • CSF2
  • CSF-2
  • GMCSF
  • GM-CSF
  • GMCSFgranulocyte-macrophage colony-stimulating factor
  • granulocyte-macrophage colony stimulating factor
  • MGC131935
  • MGC138897
  • Molgramostim
  • molgramostin
  • Sargramostim

Background

GM-CSF (Granulocyte-Macrophage Colony Stimulating Factor) induces the development of monocytes, neutrophils, eosinophils, and myeloid and dermal dendritic cells. It also acts as a neutrophil and dendritic cell chemoattractant. GM-CSF promotes Th1 and Th17 cell mediated autoimmune inflammation as well as the inflammatory activation of dendritic cells, microglia, alveolar macrophages, and eosinophils. In addition, it cooperates with G-CSF in promoting tumor cell proliferation and invasion. GM-CSF signals through a receptor complex composed of GM-CSF R alpha and the Common beta Chain (beta c) with Syndecan-2 as a potential co-receptor. The beta c subunit is shared by the receptor complexes for IL-3 and IL-5.

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⚠ WARNING: This product can expose you to chemicals including N,N-Dimethylforamide, which is known to the State of California to cause cancer. For more information, go to www.P65Warnings.ca.gov.

Publications for GM-CSF (MGM00)(27)

We have publications tested in 1 confirmed species: Mouse.


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Mouse
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Showing Publications 1 - 10 of 27. Show All 27 Publications.
Publications using MGM00 Applications Species
J Yan, Q Zhao, K Gabrusiewi, LY Kong, X Xia, J Wang, M Ott, J Xu, RE Davis, L Huo, G Rao, SC Sun, SS Watowich, AB Heimberger, S Li FGL2 promotes tumor progression in the CNS by suppressing CD103+ dendritic cell differentiation Nat Commun, 2019;10(1):448. 2019 [PMID: 30683885] (Mouse) Mouse
V Kemp, DJM van den Wo, MGM Camps, T van Hall, P Kinderman, N Pronk-van, RC Hoeben Arming oncolytic reovirus with GM-CSF gene to enhance immunity Cancer Gene Ther., 2018;0(0):. 2018 [PMID: 30467340]
W Lu, D Jia, S An, M Mu, X Qiao, Y Liu, X Li, D Wang Calf Spleen Extractive Injection protects mice against cyclophosphamide-induced hematopoietic injury through G-CSF-mediated JAK2/STAT3 signaling Sci Rep, 2017;7(1):8402. 2017 [PMID: 28827748] (Mouse) Mouse
F Reggiani, V Labanca, P Mancuso, C Rabascio, G Talarico, S Orecchioni, A Manconi, F Bertolini Adipose progenitor cell secretion of GM-CSF and MMP9 promotes a stromal and immunological microenvironment that supports breast cancer progression Cancer Res., 2017;0(0):. 2017 [PMID: 28754674] (Mouse) Mouse
K Fujiu, M Shibata, Y Nakayama, F Ogata, S Matsumoto, K Noshita, S Iwami, S Nakae, I Komuro, R Nagai, I Manabe A heart-brain-kidney network controls adaptation to cardiac stress through tissue macrophage activation Nat. Med., 2017;23(5):611-622. 2017 [PMID: 28394333] (Mouse) Mouse
N Miura, H Akita, N Tateshita, T Nakamura, H Harashima Modifying Antigen-Encapsulating Liposomes with KALA Facilitates MHC Class I Antigen Presentation and Enhances Anti-tumor Effects Mol. Ther, 2017;0(0):. 2017 [PMID: 28236573] (Mouse) Mouse
Development and Preclinical Application of an Immunocompetent Transplant Model of Basal Breast Cancer with Lung, Liver and Brain Metastases PLoS ONE, 2016;11(5):e0155262. 2016 [PMID: 27171183] (Mouse) Mouse
Sturrock, Anne, Mir-Kasimov, Mustafa, Baker, Jessica, Rowley, Jesse, Paine, Robert 3 Key role of microRNA in the regulation of granulocyte macrophage colony-stimulating factor expression in murine alveolar epithelial cells during oxidative stress. J Biol Chem, 2014;289(7):4095-105. 2014 [PMID: 24371146] (Mouse) Mouse
Goshima F, Esaki S, Luo C, Kamakura M, Kimura H, Nishiyama Y Oncolytic viral therapy with a combination of HF10, a herpes simplex virus type 1 variant and granulocyte-macrophage colony-stimulating factor for murine ovarian cancer. Int J Cancer, 2014;134(12):2865-77. 2014 [PMID: 24265099] (Mouse) Mouse
Cunha M, Lima F, Vinolo M, Hastreiter A, Curi R, Borelli P, Fock R Protein malnutrition induces bone marrow mesenchymal stem cells commitment to adipogenic differentiation leading to hematopoietic failure. PLoS ONE, 2013;8(3):e58872. 2013 [PMID: 23516566] (Mouse) Mouse
Show All 27 Publications.

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Product General Protocols

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FAQs for GM-CSF (MGM00). (Showing 1 - 1 of 1 FAQs).

  1. wondering what the difference is between your quantikine and duo set elisas?
    • Usually the duosets do not have the entire kit such as plates and buffers, whereas the other kits are complete.

Other Available Formats

HRP MGM00
HRP MGM00
HRP MGM00

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Bioinformatics

Gene Symbol Csf2