Mouse CCL20/MIP-3 alpha DuoSet ELISA, 15 Plate

• Reactivity: Mu
• Applications: ELISA
• Conjugate: Biotin

Mouse CCL20/MIP-3 alpha DuoSet ELISA, 15 Plate Summary

• Source: N/A
• Assay Type: Solid Phase Sandwich ELISA
• Inter-Assay: See PDF Datasheet for details
• Intra-Assay: See PDF Datasheet for details
• Spike Recovery: See PDF Datasheet for details
• Sample Volume: See PDF Datasheet for details
• Gene: Ccl20

Applications/Dilutions

• Dilutions:
  • ELISA
• Application Notes: No significant interference observed with available related molecules.

Packaging, Storage & Formulations

• Storage: Store the unopened product at 2 - 8 °C. Do not use past expiration date.

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for Mouse CCL20/MIP-3 alpha DuoSet ELISA, 15 Plate

• beta chemokine exodus-1
• Beta-chemokine exodus-1
• CC chemokine LARC
• C-C motif chemokine 20
• CCL20
• chemokine (C-C motif) ligand 20
• CKb4
• exodus-1
• LARC
• LARCLiver and activation-regulated chemokine
• MIP3 alpha
• MIP-3 alpha
• MIP-3a
• MIP-3-alpha
• MIP3AMacrophage inflammatory protein 3 alpha
• SCYA20Small-inducible cytokine A20
• small inducible cytokine subfamily A (Cys-Cys), member 20
• ST38

Background

CCL20, also known as MIP-3 alpha, is a chemokine that plays an important role in dendritic cell trafficking and recruitment and activation of T cells. It is upregulated in monocytes, T cells, endothelial cells, epithelial cells, and fibroblasts following inflammatory stimulation. CCL20 signals through CCR6 which is expressed on memory T cells, B cells and bone marrow-derived dendritic cells.

Publications for CCL20/MIP-3 alpha (DY760)(17)

Publications using DY760

• Pant, A;Jain, A;Chen, Y;Patel, K;Saleh, L;Tzeng, S;Nitta, RT;Zhao, L;Wu, CY;Bederson, M;Wang, WL;Bergsneider, BH;Choi, J;Medikonda, R;Verma, R;Cho, KB;Kim, LH;Kim, JE;Yazigi, E;Lee, SY;Rajendran, S;Rajappa, P;Mackall, CL;Li, G;Tyler, B;Brem, H;Pardoll, DM;Lim, M;Jackson, CM; The CCR6-CCL20 axis promotes regulatory T cell glycolysis and immunosuppression in tumors Cancer immunology research 2024-08-12 [PMID: 39133127] (Mouse)
• M Bruchard, M Geindreau, A Perrichet, C Truntzer, E Ballot, R Boidot, C Racoeur, E Barsac, F Chalmin, C Hibos, T Baranek, C Paget, B Ryffel, C Rébé, C Paul, F Végran, F Ghiringhel Recruitment and activation of type 3 innate lymphoid cells promote antitumor immune responses Nature Immunology, 2022-01-31;23(2):262-274. 2022-01-31 [PMID: 35102345] (Mouse)
• YJ Lin, A Flaczyk, S Wolfheimer, A Goretzki, A Jamin, A Wangorsch, S Vieths, S Scheurer, S Schülke The Fusion Protein rFlaA:Betv1 Modulates DC Responses by a p38-MAPK and COX2-Dependent Secretion of PGE2 from Epithelial Cells Cells, 2021-12-04;10(12):. 2021-12-04 [PMID: 34943923] (Mouse)
• L Ntari, C Nikolaou, K Kranidioti, D Papadopoul, E Christodou, P Chouvardas, F Meier, C Geka, MC Denis, N Karagianni, G Kollias Combination of subtherapeutic anti-TNF dose with dasatinib restores clinical and molecular arthritogenic profiles better than standard anti-TNF treatment Journal of Translational Medicine, 2021-04-23;19(1):165. 2021-04-23 [PMID: 33892739] (Mouse)
• D Martin-Gar, C Silva-Vilc, R Will, AH Enk, AS Lonsdorf Tumor-derived CCL20 affects B16 melanoma growth in mice J. Dermatol. Sci., 2019-12-13;0(0):. 2019-12-13 [PMID: 31883833] (Mouse)
• EM Nakada, NR Bhakta, BR Korwin-Mih, A Kumar, N Chamberlai, SR Bruno, DG Chapman, SM Hoffman, N Daphtary, M Aliyeva, CG Irvin, AE Dixon, PG Woodruff, S Amin, ME Poynter, DH Desai, V Anathy Conjugated bile acids attenuate allergen-induced airway inflammation and hyperresposiveness by inhibiting UPR transducers JCI Insight, 2019-05-02;4(9):. 2019-05-02 [PMID: 31045581] (Mouse)
• DW Wojkowska, P Szpakowski, A Glabinski Interleukin 17A Promotes Lymphocytes Adhesion and Induces CCL2 and CXCL1 Release from Brain Endothelial Cells Int J Mol Sci, 2017-05-08;18(5):. 2017-05-08 [PMID: 28481289] (Mouse)
• Ismé M de Kleer Perinatal Activation of the Interleukin-33 Pathway Promotes Type 2 Immunity in the Developing Lung Immunity, 2016-12-06;45(6):1285-1298. 2016-12-06 [PMID: 27939673] (Mouse)
• Keratinocytes contribute intrinsically to psoriasis upon loss of Tnip1 function Proc Natl Acad Sci USA, 2016-09-26;0(0):. 2016-09-26 [PMID: 27671649] (Mouse)
• Klebsiella pneumoniae Siderophores Induce Inflammation, Bacterial Dissemination, and HIF-1? Stabilization during Pneumonia MBio, 2016-09-13;7(5):. 2016-09-13 [PMID: 27624128] (Mouse)
• Brand O, Somanath S, Moermans C, Yanagisawa H, Hashimoto M, Cambier S, Markovics J, Bondesson A, Hill A, Jablons D, Wolters P, Lou J, Marks J, Baron J, Nishimura S Transforming Growth Factor-beta and Interleukin-1beta Signaling Pathways Converge on the Chemokine CCL20 Promoter. J Biol Chem, 2015-04-27;290(23):14717-28. 2015-04-27 [PMID: 25918170] (Mouse)
• Paradis M, Mindt B, Duerr C, Rojas O, Ng D, Boulianne B, McCarthy D, Yu M, Summers deLuca L, Ward L, Waldron J, Philpott D, Gommerman J, Fritz J A TNF-alpha-CCL20-CCR6 axis regulates Nod1-induced B cell responses. J Immunol, 2014-02-17;192(6):2787-99. 2014-02-17 [PMID: 24534531] (Mouse)
• Kanapathippillai P, Hedberg A, Fenton C, Fenton K Nucleosomes contribute to increase mesangial cell chemokine expression during the development of lupus nephritis. Cytokine, 2013-04-04;62(2):244-52. 2013-04-04 [PMID: 23561928] (Mouse)
• Interleukin-1alpha controls allergic sensitization to inhaled house dust mite via the epithelial release of GM-CSF and IL-33. J. Exp. Med., 2012-07-16;209(8):1505-17. 2012-07-16 [PMID: 22802353] (Mouse)
• Sheldon IM, Roberts MH Toll-like receptor 4 mediates the response of epithelial and stromal cells to lipopolysaccharide in the endometrium. PLoS ONE, 2010-09-22;5(9):e12906. 2010-09-22 [PMID: 20877575] (Mouse)
• Dittrich AM, Chen HC, Xu L, Ranney P, Connolly S, Yarovinsky TO, Bottomly HK A new mechanism for inhalational priming: IL-4 bypasses innate immune signals. J. Immunol., 2008-11-15;181(10):7307-15. 2008-11-15 [PMID: 18981153] (Mouse)
• Soboll G, Crane-Godreau MA, Lyimo MA, Wira CR Effect of oestradiol on PAMP-mediated CCL20/MIP-3 alpha production by mouse uterine epithelial cells in culture. Immunology, 2006-06-01;118(2):185-94. 2006-06-01 [PMID: 16771853] (Mouse)

FAQs for CCL20/MIP-3 alpha (DY760). (Showing 1 - 1 of 1 FAQs).

1. What is the difference between the Quantikine and Duoset ELISA kits?
   • Our Quantikine kits are fully optimized and validated for the sample types listed on the product specific webpage and datasheet, as this can vary between kits. Each kit is supplied ready to use with one pre-coated 96-well plate, a detection antibody directly conjugated to HRP, and all other necessary reagents. These kits are ideal for researchers who want the convenience of a ready to use and optimized ELISA product. Some of these kits are also available prepackaged in larger 6 and 50 plate sizes.Our DuoSet Kits, in contrast, are ELISA development kits containing the capture and detection antibody, the mass-value calibrated standard, and streptavidin-HRP to prepare approximately 5 or 15 plates. Ancillary reagents will need to be used/purchased, and for most kits, we will recommend one of our Ancillary Reagent Kits, which contain the reagents we use ourselves in-house. DuoSet kits are validated only for cell culture supernatant samples and therefore require further development and validation for accurate measurement in more complex samples such as serum and plasma. Our DuoSet Kits offer an economical, flexible alternative for the experienced ELISA user.

Bioinformatics

• Gene Symbol: Ccl20