Mouse CCL19/MIP-3 beta DuoSet ELISA, 15 Plate

• Reactivity: Mu
• Applications: ELISA
• Conjugate: Biotin

Mouse CCL19/MIP-3 beta DuoSet ELISA, 15 Plate Summary

• Source: N/A
• Assay Type: Solid Phase Sandwich ELISA
• Inter-Assay: See PDF Datasheet for details
• Intra-Assay: See PDF Datasheet for details
• Spike Recovery: See PDF Datasheet for details
• Sample Volume: See PDF Datasheet for details
• Gene: Ccl19

Applications/Dilutions

• Dilutions:
  • ELISA
• Application Notes: No significant interference observed with available related molecules.

Packaging, Storage & Formulations

• Storage: Store the unopened product at 2 - 8 °C. Do not use past expiration date.

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for Mouse CCL19/MIP-3 beta DuoSet ELISA, 15 Plate

• beta chemokine exodus-3
• Beta-chemokine exodus-3
• CC chemokine ligand 19
• C-C motif chemokine 19
• CCL19
• chemokine (C-C motif) ligand 19
• CKb11
• EBI1-ligand chemokine
• ELC
• ELCMIP-3-beta
• Epstein-Barr virus-induced molecule 1 ligand chemokine
• exodus-3
• Macrophage inflammatory protein 3 beta
• macrophage inflammatory protein 3-beta
• MGC34433
• MIP3 beta
• MIP-3 beta
• MIP-3b
• MIP3BCK beta-11
• SCYA19EBI1 ligand chemokine
• small inducible cytokine subfamily A (Cys-Cys), member 19
• Small-inducible cytokine A19

Background

Macrophage inflammatory protein 3 beta (MIP-3 beta), also known as ELC (EBI1-ligand chemokine) and exodus-3, is constitutively expressed in various lymphoid tissues, including thymus, lymph nodes, appendix and spleen. It is distantly related to other CC chemokines (20-30% amino acid sequence identity).

Publications for CCL19/MIP-3 beta (DY440)(16)

Publications using DY440

• Baek, BS;Park, H;Choi, JW;Lee, EY;Seong, SY; HIFU-CCL19/21 Axis Enhances Dendritic Cell Vaccine Efficacy in the Tumor Microenvironment Pharmaceutics 2025-01-06 [PMID: 39861713] (Mouse)
• Morgaenko, K;Arneja, A;Ball, AG;Putelo, AM;Munson, JM;Rutkowski, MR;Pompano, RR; Ex vivo model of breast cancer cell invasion in live lymph node tissue bioRxiv : the preprint server for biology 2024-07-22 [PMID: 39091774] (Mouse)
• X Niu, H Sang, J Wang Naringenin Attenuates Experimental Autoimmune Encephalomyelitis by Protecting the Intact of Blood-Brain Barrier and Controlling Inflammatory Cell Migration J Nutr Biochem, 2020-11-26;0(0):108560. 2020-11-26 [PMID: 33249188] (Mouse)
• L Liu, L Zhao, Y Yang, J Gao, C Hu, B Guo, B Zhu Cytotoxic chemotherapy reduces T cell trafficking to the spleen by downregulating the expression of C-C motif chemokine ligand 21 and C-C motif chemokine ligand 19 Oncol Lett, 2018-08-09;16(4):5013-5019. 2018-08-09 [PMID: 30250567] (Mouse)
• K Adachi, Y Kano, T Nagai, N Okuyama, Y Sakoda, K Tamada IL-7 and CCL19 expression in CAR-T cells improves immune cell infiltration and CAR-T cell survival in the tumor Nat. Biotechnol., 2018-03-05;0(0):. 2018-03-05 [PMID: 29505028] (Mouse)
• W Alturaiki, AJ McFarlane, K Rose, R Corkhill, PS McNamara, J Schwarze, BF Flanagan Expression of the B cell differentiation factor BAFF and chemokine CXCL13 in a murine model of Respiratory Syncytial Virus infection Cytokine, 2018-02-01;0(0):. 2018-02-01 [PMID: 29396045] (Mouse)
• SB Fleming, C McCaughan, Z Lateef, A Dunn, LM Wise, NC Real, AA Mercer Deletion of the Chemokine Binding Protein Gene from the Parapoxvirus Orf Virus Reduces Virulence and Pathogenesis in Sheep Front Microbiol, 2017-01-24;8(0):46. 2017-01-24 [PMID: 28174562] (Mouse)
• Yan Y, Hu K, Deng X, Guan X, Luo S, Tong L, Du T, Fu M, Zhang M, Liu Y, Hu Q Immunization with HSV-2 gB-CCL19 Fusion Constructs Protects Mice against Lethal Vaginal Challenge. J Immunol, 2015-05-20;195(1):329-38. 2015-05-20 [PMID: 25994965] (Mouse)
• Alissafi T, Hatzioannou A, Ioannou M, Sparwasser T, Grun J, Grutzkau A, Verginis P De novo-induced self-antigen-specific Foxp3+ regulatory T cells impair the accumulation of inflammatory dendritic cells in draining lymph nodes. J Immunol, 2015-05-06;194(12):5812-24. 2015-05-06 [PMID: 25948818] (Mouse)
• Lucas B, White A, Ulvmar M, Nibbs R, Sitnik K, Agace W, Jenkinson W, Anderson G, Rot A CCRL1/ACKR4 is expressed in key thymic microenvironments but is dispensable for T lymphopoiesis at steady state in adult mice. Eur J Immunol, 2015-01-16;45(2):574-83. 2015-01-16 [PMID: 25521433] (Mouse)
• Neill , Daniel R, Saint , Gemma L, Bricio-Moreno , Laura, Fothergill , Joanne L, Southern , Kevin W, Winstanley , Craig, Christmas , Stephen, Slupsky , Joseph R, McNamara , Paul S, Kadioglu , Aras, Flanagan , Brian F The B lymphocyte differentiation factor (BAFF) is expressed in the airways of children with CF and in lungs of mice infected with Pseudomonas aeruginosa. PLoS ONE, 2014-05-21;9(5):e95892. 2014-05-21 [PMID: 24847941] (Mouse)
• Paradis M, Mindt B, Duerr C, Rojas O, Ng D, Boulianne B, McCarthy D, Yu M, Summers deLuca L, Ward L, Waldron J, Philpott D, Gommerman J, Fritz J A TNF-alpha-CCL20-CCR6 axis regulates Nod1-induced B cell responses. J Immunol, 2014-02-17;192(6):2787-99. 2014-02-17 [PMID: 24534531] (Mouse)
• Yan Y, Qi S, Su L, Xu Q, Fan M Co-delivery of ccl19 gene enhances anti-caries DNA vaccine pCIA-P immunogenicity in mice by increasing dendritic cell migration to secondary lymphoid tissues. Acta Pharmacol Sin, 2013-01-21;34(3):432-40. 2013-01-21 [PMID: 23334235] (Mouse)
• Jimenez F, Quinones MP, Martinez HG, Estrada CA, Clark K, Garavito E, Ibarra J, Melby PC, Ahuja SS CCR2 plays a critical role in dendritic cell maturation: possible role of CCL2 and NF-kappa B. J. Immunol., 2010-04-19;184(10):5571-81. 2010-04-19 [PMID: 20404272] (Mouse)
• Demoor T, Bracke KR, Vermaelen KY, Dupont L, Joos GF, Brusselle GG CCR7 modulates pulmonary and lymph node inflammatory responses in cigarette smoke-exposed mice. J. Immunol., 2009-12-15;183(12):8186-94. 2009-12-15 [PMID: 19923454] (Mouse)
• Katakai T, Suto H, Sugai M, Gonda H, Togawa A, Suematsu S, Ebisuno Y, Katagiri K, Kinashi T, Shimizu A Organizer-like reticular stromal cell layer common to adult secondary lymphoid organs. J. Immunol., 2008-11-01;181(9):6189-200. 2008-11-01 [PMID: 18941209] (Mouse)

FAQs for CCL19/MIP-3 beta (DY440). (Showing 1 - 1 of 1 FAQs).

1. What is the difference between the Quantikine and Duoset ELISA kits?
   • Our Quantikine kits are fully optimized and validated for the sample types listed on the product specific webpage and datasheet, as this can vary between kits. Each kit is supplied ready to use with one pre-coated 96-well plate, a detection antibody directly conjugated to HRP, and all other necessary reagents. These kits are ideal for researchers who want the convenience of a ready to use and optimized ELISA product. Some of these kits are also available prepackaged in larger 6 and 50 plate sizes.Our DuoSet Kits, in contrast, are ELISA development kits containing the capture and detection antibody, the mass-value calibrated standard, and streptavidin-HRP to prepare approximately 5 or 15 plates. Ancillary reagents will need to be used/purchased, and for most kits, we will recommend one of our Ancillary Reagent Kits, which contain the reagents we use ourselves in-house. DuoSet kits are validated only for cell culture supernatant samples and therefore require further development and validation for accurate measurement in more complex samples such as serum and plasma. Our DuoSet Kits offer an economical, flexible alternative for the experienced ELISA user.

Bioinformatics

• Gene Symbol: Ccl19