Human CCL13/MCP-4 DuoSet ELISA, 15 Plate

• Reactivity: Hu
• Applications: ELISA
• Conjugate: Biotin

Human CCL13/MCP-4 DuoSet ELISA, 15 Plate Summary

• Assay Type: Solid Phase Sandwich ELISA
• Inter-Assay: See PDF Datasheet for details
• Intra-Assay: See PDF Datasheet for details
• Spike Recovery: See PDF Datasheet for details
• Sample Volume: See PDF Datasheet for details
• Gene: CCL13

Applications/Dilutions

• Dilutions:
  • ELISA
• Application Notes: No significant interference observed with available related molecules.

Packaging, Storage & Formulations

• Storage: Store the unopened product at 2 - 8 °C. Do not use past expiration date.

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for Human CCL13/MCP-4 DuoSet ELISA, 15 Plate

• C-C motif chemokine 13
• CCL13
• chemokine (C-C motif) ligand 13
• CKb10
• MCP4
• MCP-4
• MCP-4Monocyte chemoattractant protein 4
• MGC17134
• NCC-1Monocyte chemotactic protein 4
• NCC1Small-inducible cytokine A13
• new CC chemokine 1
• SCYA13CK-beta-10
• SCYL1
• small inducible cytokine subfamily A (Cys-Cys), member 13

Background

Human MCP-4, also known as CCL13, encodes a 98 amino acid (aa) precursor protein with a 23 aa hydrophobic signal peptide that is cleaved to yield an 8 kDa, 75 aa mature MCP-4. Mature MCP-4 lacks any potential N-glycosylation sites and shares a pyroglutamate proline motif with other human MCP proteins.

Publications for CCL13/MCP-4 (DY327)(11)

Publications using DY327

• SI Johanns, RG Gantin, B Wangala, K Komlan, WA Halatoko, M Banla, P Karabou, AJ Luty, H Schulz-Key, C Köhler, PT Soboslay Onchocerca volvulus-specific antibody and cellular responses in onchocerciasis patients treated annually with ivermectin for 30 years and exposed to parasite transmission in central Togo PloS Neglected Tropical Diseases, 2022;16(5):e0010340. 2022 [PMID: 35503786] (Human)
• W Francuzik, K Pažur, M Dalke, S Dölle-Bier, M Babina, M Worm Serological profiling reveals hsa-miR-451a as a possible biomarker of anaphylaxis JCI Insight, 2022;0(0):. 2022 [PMID: 35202004] (Human)
• B Grüner, L Peters, A Hillenbran, P Vo beta berg, J Schweiker, EG Rollmann, LH Rodriguez, J Blumhardt, S Burkert, P Kern, C Köhler, PT Soboslay Echinococcus multilocularis specific antibody, systemic cytokine, and chemokine levels, as well as antigen-specific cellular responses in patients with progressive, stable, and cured alveolar echinococcosis: A 10-year follow-up PloS Neglected Tropical Diseases, 2022;16(2):e0010099. 2022 [PMID: 35108275] (Human)
• X Li, D Guo, Y Hu, Y Chen Oxidative Stress and Inflammation Are Associated with Coexistent Severe Multivessel Coronary Artery Stenosis and Right Carotid Artery Severe Stenosis in Elderly Patients Oxidative Medicine and Cellular Longevity, 2021;2021(0):2976447. 2021 [PMID: 34976297] (Human)
• Himes B, Koziol-White C, Johnson M, Nikolos C, Jester W, Klanderman B, Litonjua A, Tantisira K, Truskowski K, MacDonald K, Panettieri R, Weiss S Vitamin D Modulates Expression of the Airway Smooth Muscle Transcriptome in Fatal Asthma. PLoS ONE, 2015;10(7):e0134057. 2015 [PMID: 26207385] (Human)
• Lechner C, Komander K, Hegewald J, Huang X, Gantin R, Soboslay P, Agossou A, Banla M, Kohler C Cytokine and chemokine responses to helminth and protozoan parasites and to fungus and mite allergens in neonates, children, adults, and the elderly. Immun Ageing, 2013;10(1):29. 2013 [PMID: 23855879] (Human)
• Krausgruber T, Blazek K, Smallie T IRF5 promotes inflammatory macrophage polarization and T(H)1-T(H)17 responses. Nat. Immunol., 2011;12(3):231-8. 2011 [PMID: 21240265] (Human)
• Ockinger J, Stridh P, Beyeen AD, Lundmark F, Seddighzadeh M, Oturai A, Sorensen PS, Lorentzen AR, Celius EG, Leppa V, Koivisto K, Tienari PJ, Alfredsson L, Padyukov L, Hillert J, Kockum I, Jagodic M, Olsson T Genetic variants of CC chemokine genes in experimental autoimmune encephalomyelitis, multiple sclerosis and rheumatoid arthritis. Genes Immun., 2010;11(2):142-54. 2010 [PMID: 19865101] (Human)
• Yanaba K, Yoshizaki A, Muroi E, Hara T, Ogawa F, Shimizu K, Hasegawa M, Fujimoto M, Takehara K, Sato S CCL13 is a promising diagnostic marker for systemic sclerosis. Br. J. Dermatol., 2010;162(2):332-6. 2010 [PMID: 19747218] (Human)
• Eagan TM, Ueland T, Wagner PD, Hardie JA, Mollnes TE, Damas JK, Aukrust P, Bakke PS Systemic inflammatory markers in COPD: results from the Bergen COPD Cohort Study. Eur. Respir. J., 2010;35(3):540-8. 2010 [PMID: 19643942] (Human)
• Hintzen C, Quaiser S, Pap T, Heinrich PC, Hermanns HM Induction of CCL13 expression in synovial fibroblasts highlights a significant role of oncostatin M in rheumatoid arthritis. Arthritis Rheum., 2009;60(7):1932-43. 2009 [PMID: 19565514] (Human)

Bioinformatics

• Gene Symbol: CCL13