Mouse CCL11/Eotaxin DuoSet ELISA, 15 Plate

• Reactivity: Mu
• Applications: ELISA
• Conjugate: Biotin

Mouse CCL11/Eotaxin DuoSet ELISA, 15 Plate Summary

• Source: N/A
• Assay Type: Solid Phase Sandwich ELISA
• Inter-Assay: See PDF Datasheet for details
• Intra-Assay: See PDF Datasheet for details
• Spike Recovery: See PDF Datasheet for details
• Sample Volume: See PDF Datasheet for details
• Gene: Ccl11

Applications/Dilutions

• Dilutions:
  • ELISA
• Application Notes: No significant interference observed with available related molecules.

Packaging, Storage & Formulations

• Storage: Store the unopened product at 2 - 8 °C. Do not use past expiration date.

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for Mouse CCL11/Eotaxin DuoSet ELISA, 15 Plate

• C-C motif chemokine 11
• CCL11
• chemokine (C-C motif) ligand 11
• Eosinophil chemotactic protein
• Eotaxin
• eotaxin-1
• MGC22554
• SCYA11Small-inducible cytokine A11
• small inducible cytokine subfamily A (Cys-Cys), member 11 (eotaxin)

Background

CCL11/Eotaxin is a chemokine that interacts with CCR3 to induce eosinophil, basophil, dendritic cell, and Th2 cell chemoattraction during inflammatory and allergic reactions. Its production is upregulated in airway epithelium, alveolar macrophages, eosinophils, smooth muscle cells, chondrocytes, and fibroblasts following allergen or inflammatory challenge. CCL11 is also involved in the growth of myeloid cell progenitors and the differentiation of mast cells.

Publications for CCL11/Eotaxin (DY420)(31)

Publications using DY420

• Scheunemann, JF;Risch, F;Reichwald, JJ;Lenz, B;Neumann, AL;Garbe, S;Frohberger, SJ;Koschel, M;Ajendra, J;Rothe, M;Latz, E;Coch, C;Hartmann, G;Schumak, B;Hoerauf, A;H�bner, MP; Potential of Nucleic Acid Receptor Ligands to Improve Vaccination Efficacy against the Filarial Nematode Litomosoides sigmodontis Vaccines 2023-05-10 [PMID: 37243070] (Mouse)
• S Rutecki, P Szulc, M Paku?a, P Uruski, A Radziemski, E Naumowicz, R Moszy?ski, A Tykarski, J Miku?a-Pie, K Ksi??ek Pro-cancerogenic effects of spontaneous and drug-induced senescence of ovarian cancer cells in vitro and in vivo: a comparative analysis Journal of ovarian research, 2022-07-26;15(1):87. 2022-07-26 [PMID: 35883110] (Human)
• MD Ihrie, VL McQuade, JT Womble, A Hegde, MS McCravy, CVG Lacuesta, RM Tighe, LG Que, JKL Walker, JL Ingram Exogenous leptin enhances markers of airway fibrosis in a mouse model of chronic allergic airways disease Respiratory Research, 2022-05-24;23(1):131. 2022-05-24 [PMID: 35610699] (Mouse)
• SR Bruno, A Kumar, ZF Mark, R Chandrasek, E Nakada, N Chamberlai, B Mihavics, J Walzer, J Cahoon, AE Dixon, B Cunniff, V Anathy DRP1-Mediated Mitochondrial Fission Regulates Lung Epithelial Response to Allergen International Journal of Molecular Sciences, 2021-10-15;22(20):. 2021-10-15 [PMID: 34681784] (Mouse)
• JQ Yang, KW Kalim, Y Li, Y Zheng, F Guo Ablation of RhoA impairs Th17 cell differentiation and alleviates house dust mite-triggered allergic airway inflammation J. Leukoc. Biol., 2019-07-01;0(0):. 2019-07-01 [PMID: 31260596] (Mouse)
• EM Nakada, NR Bhakta, BR Korwin-Mih, A Kumar, N Chamberlai, SR Bruno, DG Chapman, SM Hoffman, N Daphtary, M Aliyeva, CG Irvin, AE Dixon, PG Woodruff, S Amin, ME Poynter, DH Desai, V Anathy Conjugated bile acids attenuate allergen-induced airway inflammation and hyperresposiveness by inhibiting UPR transducers JCI Insight, 2019-05-02;4(9):. 2019-05-02 [PMID: 31045581] (Mouse)
• CC Campa, RL Silva, JP Margaria, T Pirali, MS Mattos, LR Kraemer, DC Reis, G Grosa, F Copperi, EM Dalmarco, RCP Lima-Júnio, S Aprile, V Sala, F Dal Bello, DS Prado, JC Alves-Filh, C Medana, GD Cassali, GC Tron, MM Teixeira, E Ciraolo, RC Russo, E Hirsch Inhalation of the prodrug PI3K inhibitor CL27c improves lung function in asthma and fibrosis Nat Commun, 2018-12-12;9(1):5232. 2018-12-12 [PMID: 30542075] (Mouse)
• MF Serra, AC Cotias, CRR Pão, JB Daleprane, PB Jurgilas, GC Couto, EA Anjos-Valo, RSB Cordeiro, VF Carvalho, PMR Silva, MA Martins Repeated Allergen Exposure in A/J Mice Causes Steroid-Insensitive Asthma via a Defect in Glucocorticoid Receptor Bioavailability J. Immunol., 2018-06-18;0(0):. 2018-06-18 [PMID: 29914889] (Mouse)
• CFCG Nunes, JS Nogueira, FB Canto, PHO Vianna, BT Ciambarell, PMRE Silva, KR Miranda, LA Lobo, RMCP Domingues, M Busch, GC Atella, AM Vale, M Bellio, A Nóbrega, R Fucs Probiotic treatment during neonatal age provides optimal protection against experimental asthma through the modulation of microbiota and T cells: Neonatal exposure to probiotics prevents asthma Int. Immunol., 2018-04-03;0(0):. 2018-04-03 [PMID: 29420746] (ELISA Capture, Mouse)
• S Qiu, X Fan, Y Yang, P Dong, W Zhou, Y Xu, Y Zhou, F Guo, Y Zheng, JQ Yang Schistosoma japonicum infection downregulates house dust mite-induced allergic airway inflammation in mice PLoS ONE, 2017-06-14;12(6):e0179565. 2017-06-14 [PMID: 28614408] (Mouse)
• SU Venkatesha, X Zhu, P Rajavelu, R Niranjan, M Manohar, AK Verma, JA Lasky, A Mishra Regulatory effects of Interleukin (IL)-15 on allergen-induced airway obstruction J. Allergy Clin. Immunol., 2017-06-09;0(0):. 2017-06-09 [PMID: 28606589] (Mouse)
• Ingrid Stroo Factor XI deficiency enhances the pulmonary allergic response to house dust mite in mice independent of factor XII Am. J. Physiol. Lung Cell Mol. Physiol, 2016-12-02;0(0):ajplung.00320. 2016-12-02 [PMID: 27913422] (Mouse)
• Regulation of eosinophilia and allergic airway inflammation by the glycan-binding protein galectin-1 Proc Natl Acad Sci USA, 2016-07-25;0(0):. 2016-07-25 [PMID: 27457925] (Mouse)
• Netali Ben Baruch Paired Ig-like Receptor B Inhibits IL-13-Driven Eosinophil Accumulation and Activation in the Esophagus J Immunol, 2016-06-20;0(0):. 2016-06-20 [PMID: 27324131] (Mouse)
• Post , Sijranke, Heijink , Irene H, Petersen , Arjen H, de Bruin , Harold G, van Oosterhout , Antoon J, Nawijn , Martijn Protease-activated receptor-2 activation contributes to house dust mite-induced IgE responses in mice. PLoS ONE, 2014-03-20;9(3):e91206. 2014-03-20 [PMID: 24651123] (Mouse)
• Malmhall C, Alawieh S, Lu Y, Sjostrand M, Bossios A, Eldh M, Radinger M MicroRNA-155 is essential for T(H)2-mediated allergen-induced eosinophilic inflammation in the lung. J Allergy Clin Immunol, 2013-12-24;133(5):1429-38, 1438. 2013-12-24 [PMID: 24373357] (Mouse)
• Kiwamoto T, Brummet M, Wu F, Motari M, Smith D, Schnaar R, Zhu Z, Bochner B Mice deficient in the St3gal3 gene product alpha2,3 sialyltransferase (ST3Gal-III) exhibit enhanced allergic eosinophilic airway inflammation. J Allergy Clin Immunol, 2013-07-02;133(1):240-7.e1-3. 2013-07-02 [PMID: 23830412] (Mouse)
• Waddell A, Ahrens R, Tsai Y, Sherrill J, Denson L, Steinbrecher K, Hogan S Intestinal CCL11 and eosinophilic inflammation is regulated by myeloid cell-specific RelA/p65 in mice. J Immunol, 2013-04-05;190(9):4773-85. 2013-04-05 [PMID: 23562811] (Mouse)
• Paulissen G, El Hour M, Rocks N, Gueders M, Bureau F, Foidart J, Lopez-Otin C, Noel A, Cataldo D Control of allergen-induced inflammation and hyperresponsiveness by the metalloproteinase ADAMTS-12. J Immunol, 2012-09-07;189(8):4135-43. 2012-09-07 [PMID: 22962682] (Mouse)
• Veliz Rodriguez T, Moalli F, Polentarutti N, Paroni M, Bonavita E, Anselmo A, Nebuloni M, Mantero S, Jaillon S, Bragonzi A, Mantovani A, Riva F, Garlanda C Role of Toll interleukin-1 receptor (IL-1R) 8, a negative regulator of IL-1R/Toll-like receptor signaling, in resistance to acute Pseudomonas aeruginosa lung infection. Infect. Immun., 2011-10-24;80(1):100-9. 2011-10-24 [PMID: 22025515] (Mouse)
• Chuang YH, Wang TC, Jen HY, Yu AL, Chiang BL Alpha-Galactosylceramide-induced airway eosinophilia is mediated through the activation of NKT cells. J. Immunol., 2011-03-07;186(8):4687-92. 2011-03-07 [PMID: 21383248] (Mouse)
• Bourgeois EA, Levescot A, Diem S, Chauvineau A, Berges H, Milpied P, Lehuen A, Damotte D, Gombert JM, Schneider E, Girard JP, Gourdy P, Herbelin A A natural protective function of invariant NKT cells in a mouse model of innate-cell-driven lung inflammation. Eur. J. Immunol., 2011-01-11;41(2):299-305. 2011-01-11 [PMID: 21268000] (Mouse)
• van Neerven S, Regen T, Wolf D, Nemes A, Johann S, Beyer C, Hanisch UK, Mey J Inflammatory chemokine release of astrocytes in vitro is reduced by all-trans retinoic acid. J. Neurochem., 2010-06-16;114(5):1511-26. 2010-06-16 [PMID: 20557428] (Mouse)
• Zhu M, Hug C, Kasahara DI Impact of adiponectin deficiency on pulmonary responses to acute ozone exposure in mice. Am. J. Respir. Cell Mol. Biol., 2009-11-13;43(4):487-97. 2009-11-13 [PMID: 19915153] (Mouse)
• Neveu WA, Allard JB, Dienz O, Wargo MJ, Ciliberto G, Whittaker LA, Rincon M IL-6 is required for airway mucus production induced by inhaled fungal allergens. J. Immunol., 2009-07-10;183(3):1732-8. 2009-07-10 [PMID: 19592651] (Mouse)
• Brandt EB, Mingler MK, Stevenson MD, Wang N, Khurana Hershey GK, Whitsett JA, Rothenberg ME Surfactant protein D alters allergic lung responses in mice and human subjects. J. Allergy Clin. Immunol., 2008-03-19;121(5):1140-1147.e2. 2008-03-19 [PMID: 18355911] (Mouse)
• Min MG, Song DJ, Miller M, Cho JY, McElwain S, Ferguson P, Broide DH Coexposure to environmental tobacco smoke increases levels of allergen-induced airway remodeling in mice. J. Immunol., 2007-04-15;178(8):5321-8. 2007-04-15 [PMID: 17404317] (Mouse)
• D'Avila H, Almeida PE, Roque NR, Castro-Faria-Neto HC, Bozza PT Toll-like receptor-2-mediated C-C chemokine receptor 3 and eotaxin-driven eosinophil influx induced by Mycobacterium bovis BCG pleurisy. Infect. Immun., 2006-12-11;75(3):1507-11. 2006-12-11 [PMID: 17158890] (Mouse)
• Schnyder-Candrian S, Togbe D, Couillin I, Mercier I, Brombacher F, Quesniaux V, Fossiez F, Ryffel B, Schnyder B Interleukin-17 is a negative regulator of established allergic asthma. J. Exp. Med., 2006-11-13;203(12):2715-25. 2006-11-13 [PMID: 17101734] (Mouse)
• Kouznetsova I, Chwieralski CE, Balder R, Hinz M, Braun A, Krug N, Hoffmann W Induced trefoil factor family 1 expression by trans-differentiating Clara cells in a murine asthma model. Am. J. Respir. Cell Mol. Biol., 2006-09-21;36(3):286-95. 2006-09-21 [PMID: 16990615] (Mouse)
• Lu FL, Johnston RA, Flynt L, Theman TA, Terry RD, Schwartzman IN, Lee A, Shore SA Increased pulmonary responses to acute ozone exposure in obese db/db mice. Am. J. Physiol. Lung Cell Mol. Physiol., 2005-12-22;290(5):L856-65. 2005-12-22 [PMID: 16373670] (Mouse)

Review for CCL11/Eotaxin (DY420) (1)

Average Rating: 5

(Based on 1 review)

reviewed by: Verified Customer 01/17/2025

Summary

• Sample Tested: mouse serum
• Lot: P405474

Bioinformatics

• Gene Symbol: Ccl11