Mindin/Spondin-2 Antibody [Biotin]

• Reactivity: Hu
• Applications: WB
• Clonality: Polyclonal
• Host: Goat
• Conjugate: Biotin
• Concentration: LYOPH

Mindin/Spondin-2 Antibody [Biotin] Summary

• Immunogen: Mouse myeloma cell line NS0-derived recombinant human Mindin
  Glu32-Val331
  Accession # Q9BUD6
• Specificity: Detects human Mindin in Western blots.
• Source: N/A
• Isotype: IgG
• Clonality: Polyclonal
• Host: Goat
• Gene: SPON2
• Purity Statement: Antigen Affinity-purified

Applications/Dilutions

• Dilutions:
  • Western Blot 0.1 ug/mL
• Readout System:
  • Streptavidin Native Protein NBP2-29367
  • Streptavidin Native Protein NBP2-29370
  • Streptavidin Native Protein NBP2-29371

Packaging, Storage & Formulations

• Storage: Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
  12 months from date of receipt, -20 to -70 degreesC as supplied. 1 month, 2 to 8 degreesC under sterile conditions after reconstitution. 6 months, -20 to -70 degreesC under sterile conditions after reconstitution.
• Buffer: Lyophilized from a 0.2 μm filtered solution in PBS with BSA as a carrier protein.
• Preservative: No Preservative
• Concentration: LYOPH
• Reconstitution Instructions: Reconstitute at 0.2 mg/mL in sterile PBS.

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for Mindin/Spondin-2 Antibody [Biotin]

• Differentially expressed in cancerous and non-cancerous lung cells 1
• DIL1
• DIL-1
• DIL1FLJ34460
• DKFZp686G21139
• FLJ16313
• FLJ22401
• Mindin
• M-SPONDIN
• RG-1
• SPON2
• Spondin 2
• spondin 2, extracellular matrix protein
• spondin-2

Background

Mindin, also known as Spondin-2 and DIL-1 (Differentially expressed in cancerous and non-cancerous lung cells 1) belongs to the F-spondin family of secreted extracellular matrix proteins. Family members are characterized by two N-terminal F-spondin domains (FS1 and FS2), and a third C-terminal thrombospondin type I repeat (TSP-1). Secreted Mindin exists as a disulfide-linked dimer that also forms higher order oligomers. It functions as a pattern recognition receptor for microbes and an adhesion molecule for neurons. Mindin is secreted by neurons, macrophages and fibroblasts in a variety of tissues. Human Mindin shares 88% amino acid sequence homology with mouse and rat proteins.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: SPON2
• Uniprot:
  • Q9BUD6()