METTL7B Antibody

Images

 
Western Blot: METTL7B Antibody [NBP1-77337] - Analysis of MettL7B in human colon tissue lysate with MettL7B antibody at (A) 1 and (B) 2 ug/mL.
Immunohistochemistry-Paraffin: METTL7B Antibody [NBP1-77337] - Human spleen tissue with MettL7B antibody at 2.5 ug/ml.
Western Blot: METTL7B Antibody [NBP1-77337] - Jurkat lysate with MettL7B antibody at (A) 2 and (B) 4 ug/mL.

Product Details

Summary
Reactivity Hu, MuSpecies Glossary
Applications WB, ELISA, IHC, IHC-P
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated
Concentration
1 mg/ml

Order Details

METTL7B Antibody Summary

Immunogen
Antibody was raised against a 13 amino acid synthetic peptide near the amino terminus of human MettL7B. The immunogen is located within amino acids 20 - 70 of MettL7B.
Specificity
This MettL7B antibody is predicted to not cross-react with MettL7A.
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
METTL7B
Purity
Immunogen affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Western Blot 1:100-1:2000
  • ELISA 1:100-1:2000
  • Immunohistochemistry 1:10-1:500
  • Immunohistochemistry-Paraffin 1:10-1:500
Theoretical MW
27 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.
Control Peptide
METTL7B Peptide (NBP1-77337PEP)

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS
Preservative
0.02% Sodium Azide
Concentration
1 mg/ml
Purity
Immunogen affinity purified

Alternate Names for METTL7B Antibody

  • EC 2.1.1
  • EC 2.1.1.-
  • methyltransferase like 7B
  • methyltransferase-like protein 7B
  • MGC17301

Background

MettL7B belongs to the methyltransferase superfamily. It is a probable methyltransferase. Methyltransferase is a type of transferase enzyme which transfers a methyl group from a donor to an acceptor. Often methylation occurs on nucleic bases in DNA or amino acids in protein structures. DNA methylation is often utilized to silence and regulate genes without changing the original DNA sequence. DNA methylation may be necessary for normal growth from embryonic stages in mammals. When mutant embryonic stem cells lacking the murine DNA methyltransferase gene were introduced to a germline of mice they caused a recessive lethal phenotype. Methylation may also be linked to cancer development as methylation of tumor suppressor genes promotes tumorgenesis and metastasis. This MettL7B antibody is predicted to not cross-react with MettL7A.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Secondary Antibodies

 

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Bioinformatics

Gene Symbol METTL7B
Uniprot