METTL7B Antibody - BSA Free

Western Blot: METTL7B Antibody [NBP1-77337] - Analysis of MettL7B in human colon tissue lysate with MettL7B antibody at (A) 1 and (B) 2 ug/mL.

Immunohistochemistry: METTL7B Antibody - BSA Free [NBP1-77337] - Immunohistochemistry of METTL7B in human spleen tissue with METTL7B antibody at 2.5 ug/mL.

• Reactivity: Hu, Mu
• Applications: WB, ELISA, IHC
• Clonality: Polyclonal
• Host: Rabbit
• Conjugate: Unconjugated
• Format: BSA Free
• Concentration: 1 mg/ml

METTL7B Antibody - BSA Free Summary

• Description: Novus Biologicals Rabbit METTL7B Antibody - BSA Free (NBP1-77337) is a polyclonal antibody validated for use in IHC, WB and ELISA. All Novus Biologicals antibodies are covered by our 100% guarantee.
• Immunogen: Antibody was raised against a 13 amino acid synthetic peptide near the amino terminus of human MettL7B. The immunogen is located within amino acids 20 - 70 of MettL7B. Amino Acid Squence: VLTPKSNRKMESK
• Specificity: This MettL7B antibody is predicted to not cross-react with MettL7A.
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: TMT1B
• Purity: Peptide affinity purified

Applications/Dilutions

• Dilutions:
  • ELISA 1:100-1:2000
  • Immunohistochemistry 2.5 ug/ml
  • Immunohistochemistry-Paraffin 2.5 ug/ml
  • Western Blot 1-2 ug/ml
• Theoretical MW: 27 kDa.
  Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.
• Control Peptide:

  METTL7B Peptide (NBP1-77337PEP)

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: PBS
• Preservative: 0.02% Sodium Azide
• Concentration: 1 mg/ml
• Purity: Peptide affinity purified

Alternate Names for METTL7B Antibody - BSA Free

• EC 2.1.1
• EC 2.1.1.-
• methyltransferase like 7B
• methyltransferase-like protein 7B
• MGC17301

Background

MettL7B belongs to the methyltransferase superfamily. It is a probable methyltransferase. Methyltransferase is a type of transferase enzyme which transfers a methyl group from a donor to an acceptor. Often methylation occurs on nucleic bases in DNA or amino acids in protein structures. DNA methylation is often utilized to silence and regulate genes without changing the original DNA sequence. DNA methylation may be necessary for normal growth from embryonic stages in mammals. When mutant embryonic stem cells lacking the murine DNA methyltransferase gene were introduced to a germline of mice they caused a recessive lethal phenotype. Methylation may also be linked to cancer development as methylation of tumor suppressor genes promotes tumorgenesis and metastasis. This MettL7B antibody is predicted to not cross-react with MettL7A.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: TMT1B
• Uniprot:
  • NP_689850(Human)