Meteorin Antibody (347511)

• Reactivity: Mu
• Applications: ELISA(Cap)
• Clone: 347511
• Clonality: Monoclonal
• Host: Rat
• Conjugate: Unconjugated

Meteorin Antibody (347511) Summary

• Immunogen: Mouse myeloma cell line NS0-derived recombinant mouse Meteorin
  Gly22-Asp291
  Accession # Q8C1Q4
• Specificity: Detects mouse Meteorin in ELISAs.In sandwich immunoassays, no cross-reactivity or interference with recombinant mouse CDNF, recombinant rat (rr) CNTF, or rrGDNF is observed.
• Source: N/A
• Isotype: IgG2a
• Clonality: Monoclonal
• Host: Rat
• Gene: Metrn
• Purity Statement: Protein A or G purified from hybridoma culture supernatant

Applications/Dilutions

• Dilutions:
  • ELISA Capture (Matched Antibody Pair) 2-8 ug/mL
  • ELISA Detection (Matched Antibody Pair) 0.5-2 ug/mL
  • ELISA Standard (Matched Pair)
• Application Notes: ELISA Detection: Mouse Meteorin Biotinylated Antibody (Catalog number BAM34751)
  Standard: Recombinant Mouse Meteorin (Catalog number 3475-MN)

Packaging, Storage & Formulations

• Storage: Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
  • 12 months from date of receipt, -20 to -70 °C as supplied.
  • 1 month, 2 to 8 °C under sterile conditions after reconstitution.
  • 6 months, -20 to -70 °C under sterile conditions after reconstitution.
• Buffer: Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.
• Preservative: No Preservative
• Reconstitution Instructions: Sterile PBS to a final concentration of 0.5 mg/mL.

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for Meteorin Antibody (347511)

• C16orf23
• c380A1.2
• Meteorin
• METRN

Background

Meteorin is a 31 kDa, secreted protein that is expressed by undifferentiated neural and glial progenitors, and astrocytes. Its name derives from it ability to generate glial cells with long meteor-like tails. Mouse Meteorin is synthesized as a 291 amino acid (aa) precursor that contains a 270 aa mature region. It contains eight cysteines with no identifiable domains or N-linked glycosylation sites. There is one alternate splice form where the first 164 aa of the precursor are deleted and aa 165 is changed to a Met, possibly to serve in translation initiation. Mature mouse Meteorin is 82% and 77% aa identical to human and bovine Meteorin, respectively.  

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: Metrn
• Uniprot:
  • Q8C1Q4(Mouse)