Mena Antibody (ENAH/1988) [DyLight 680]

• Reactivity: Hu
• Applications: WB, ELISA, MA
• Clone: ENAH/1988
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: DyLight 680

Mena Antibody (ENAH/1988) [DyLight 680] Summary

• Immunogen: Recombinant fragment of human Mena protein (around aa 485-589) (exact sequence is proprietary) (Uniprot: Q8N8S7)
• Localization: Cytoplasmic
• Isotype: IgG2c Kappa
• Clonality: Monoclonal
• Host: Mouse
• Gene: ENAH
• Purity: Protein A or G purified

Applications/Dilutions

• Dilutions:
  • ELISA
  • Protein Array
  • Western Blot
• Application Notes: Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

• Storage: Store at 4C in the dark.
• Buffer: 50mM Sodium Borate
• Preservative: 0.05% Sodium Azide
• Purity: Protein A or G purified

Notes

DyLight (R) is a trademark of Thermo Fisher Scientific Inc. and its subsidiaries.

Alternate Names for Mena Antibody (ENAH/1988) [DyLight 680]

• ENA
• enabled homolog (Drosophila)
• ENAH
• FLJ10773
• Mena
• MENANDPP1
• NDPP1
• protein enabled homolog

Background

ENAH/MENA belongs to the Ena/vasodilator-stimulated phosphoprotein (VASP) family of proteins which play a role in regulating the actin cytoskeleton for the control of cell shape and movement. The Ena/VASP family of actin binding proteins includes ENAH/MENA which is the human homolog of drosophila Ena (enabled), VASP, and EVL (Ena/vasodilator-stimulated phosphoprotein-like protein). Ena/VASP proteins contain an EVH1 domain, a central proline-rich domain, and a terminal EVH2 domain. ENAH/MENA is not expressed in normal breast but has been detected and associated with breast lesions with a high risk of transformation and primary and metastatic breast cancer.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: ENAH