mediator of cell motility 1 Antibody (1E9) - BSA Free

Western Blot: mediator of cell motility 1 Antibody (1E9) [NBP2-22593] - The cell lysates of Jurkat (40ug) were resolved by SDS-PAGE, transferred to PVDF membrane and probed with anti-human MEMO1 antibody (1:3000). Proteins were visualized using a goat anti-mouse secondary antibody conjugated to HRP and an ECL detection system.

• Reactivity: Hu
• Applications: WB, ELISA, Flow
• Clone: 1E9
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: Unconjugated
• Format: BSA Free
• Concentration: 1 mg/ml

mediator of cell motility 1 Antibody (1E9) - BSA Free Summary

• Description: Novus Biologicals Mouse mediator of cell motility 1 Antibody (1E9) - BSA Free (NBP2-22593) is a monoclonal antibody validated for use in WB, ELISA and Flow. All Novus Biologicals antibodies are covered by our 100% guarantee.
• Immunogen: Recombinant human mediator of cell motility 1 (1-297aa) purified from E. coli
• Isotype: IgG1 Kappa
• Clonality: Monoclonal
• Host: Mouse
• Gene: MEMO1
• Purity: Protein G purified

Applications/Dilutions

• Dilutions:
  • ELISA 1:100-1:2000
  • Flow Cytometry
  • Western Blot 1:3000

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: PBS (pH 7.4), 10% Glycerol
• Preservative: 0.02% Sodium Azide
• Concentration: 1 mg/ml
• Purity: Protein G purified

Alternate Names for mediator of cell motility 1 Antibody (1E9) - BSA Free

• C21orf19-like protein
• C2orf4DKFZp434I0135
• CGI-27
• FLJ25031
• HCV NS5A-transactivated protein 7
• Hepatitis C virus NS5A-transactivated protein 7
• mediator of cell motility 1
• Mediator of ErbB2-driven cell motility 1
• memo-1
• MEMOchromosome 2 open reading frame 4
• NS5ATP7
• protein MEMO1

Background

MEMO1 (Mediator of ErbB2-driven cell motility 1) is a 297 amino acid protein. It is thought to relax extracellular chemotactic signals that are targeted at the microtubule cytoskeleton, thereby controlling cell migration. Additionally, MEMO1 is required for breast carcinoma migration, suggesting an important role in tumorigenesis. The MEMO1-RHOA-DIAPH1 signaling pathway plays an important role in ERBB2-dependent stabilization of microtubules at the cell cortex. It controls the localization of APC and CLASP2 to the cell membrane, via the regulation of GSK3B activity

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: MEMO1
• Uniprot:
  • NP_057039(Human)