MDMX Antibody [Biotin]

Product Discontinued

MDMX Antibody [Biotin] Summary

• Immunogen: The immunogen recognized by this antibody maps to a region between residues 125 and 175 of human ortholog of mouse double minute 4 using the numbering given in Swiss-Prot entry O15151 (GeneID 4194).
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: MDM4
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • Immunoprecipitation 2 -5 ug/mg lysate
  • Western Blot 1:10000-1:25000
• Readout System:
  • Streptavidin Native Protein NBP2-29367
  • Streptavidin Native Protein NBP2-29370
  • Streptavidin Native Protein NBP2-29371

Packaging, Storage & Formulations

• Storage: Store at 4C. Do not freeze.
• Buffer: PBS and 0.2% BSA
• Preservative: 0.09% Sodium Azide
• Concentration: LYOPH
• Purity: Immunogen affinity purified
• Reconstitution Instructions: Reconstitute with 0.1 ml deionized water.

Alternate Names for MDMX Antibody [Biotin]

• DKFZp781B1423
• double minute 4 homolog
• Double minute 4 protein
• double minute 4, human homolog of; p53-binding protein
• HDMX
• Mdm2-like p53-binding protein
• Mdm4 p53 binding protein homolog (mouse)
• MDM4 Regulator of P53
• MDM4
• Mdm4, transformed 3T3 cell double minute 4, p53 binding protein (mouse)
• Mdm4, transformed 3T3 cell double minute 4, p53 binding protein
• MDM4-related protein 1
• MDMX
• MDMXMGC132766
• mouse double minute 4, human homolog of; p53-binding protein
• MRP1
• p53-binding protein Mdm4
• protein Mdm4
• Protein Mdmx

Background

Mdm4 p53 binding protein homolog (mouse). The human MDM4 gene, which plays a role in apoptosis, encodes a 490-amino acid protein containing a RING finger domain and a putative nuclear localization signal. The MDM4 putative nuclear localization signal, which all Mdm proteins contain, is located in the C-terminal region of the protein. The mRNA is expressed at a high level in thymus and at lower levels in all other tissues tested. MDM4 protein produced by in vitro translation interacts with p53 via a binding domain located in the N-terminal region of the MDM4 protein. MDM4 shows significant structural similarity to p53-binding protein MDM2

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: MDM4
• Entrez:
  • 4194(Human)
• Uniprot:
  • O15151(Human)